Research Article

Bradykinin Type-2 Receptor Expression Correlates with Age and Is Subjected to Transcriptional Regulation

Table 1

BK-2R polymorphism in human hearts. The presence of two BK-2R gene polymorphisms, −58T/C and −9/+9, was analyzed in normal and failing human hearts according to the protocol described in Section 2.

Subject no.EtiologySexAgePolymorphism
−58 T/C+9/−9

1NormalM19T/C+9/−9
2M43T/C+9/+9
3M49C/C+9/−9
4M31T/T−9/−9
5M40T/C+9/+9
6F50C/C+9/−9

7CHDM61T/C−9/−9
8M60T/T−9/−9
9M55C/C−9/−9
10M52T/C−9/−9
11M60C/C−9/−9
12M54T/C−9/−9

13IDCM29C/C−9/−9
14M60C/C−9/−9
15M46C/C+9/−9
16M56C/C+9/−9
17M55T/T+9/−9
18M56T/C+9/−9
19M63C/C+9/−9