Chronic C-Type Natriuretic Peptide Infusion Attenuates Angiotensin II-Induced Myocardial Superoxide Production and Cardiac Remodeling

Figure 1

Effects of CNP on echocardiographic measurements. (a) Representative M-mode echocardiogram of vehicle- and CNP-treated mice 2 weeks after saline or Ang II infusion. (b) Interventricular septum (IVS) and posterior wall thickness (PWT) in vehicle- and CNP-treated mice 2 weeks after saline or Ang II infusion. (c) Left ventricular end-diastolic dimension (LVEDD) and fractional shortening (%FS) in vehicle- and CNP-treated mice 2 weeks after saline or Ang II infusion. Results are mean ± SEM (𝑛=3–6 each). *𝑃<0.05.

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