Clinical Study

The Influence of Endothelial Function and Myocardial Ischemia on Peak Oxygen Consumption in Patients with Coronary Artery Disease

Table 3

Endothelial function variables and ischemia predicting peak oxygen consumption (VO2) during exercise testing, adjusting for vessel size, medication status during the FMD test, age, and BMI.

VariableModel 1Model 2Model 3Model 4

Ischemia −0.02.860−0.12.433−0.04.970−0.31.189
FMD0.04.006−0.01.866
FMD × ischemia0.03.382
GTNMD0.02.019−0.01.546
GTNMD × ischemia0.02.151

FMD: flow-mediated dilatation, GTNMD: GTN-mediated dilatation
Note: value labeled is the unstandardized regression coefficient from mixed model. Ischemia was scored as ischemia = 1 and no-ischemia = 2. Dash indicates that the variable was not included in the model. Model 1 refers to main effect of FMD and ischemia on peak VO2, Model 2 refers to their interaction effects on peak VO2, Model 3 represents the main effects of GTNMD and ischemia on peak VO2, and Model 4 represents their interaction effects on peak VO2.