Review Article

Blood Flow Restricted Exercise and Vascular Function

Table 1

Acute effects of blood flow restricted exercise on vascular function and related biomarkers.

Author & yearSubjectsAge
(yrs)
Applied cuff
pressure (mmHg)
Intensity or
velocity
Reps, sets,
or time
Exercise
modality
Occlusion
time (min)
Cuff width (cm)OutcomeEffect

Renzi et al. (2010) [139] 11 men
6 women
261602 miles/h10 minwalking1424FMD
Fahs et al. (2011) [124] 11 men2820020% 1 RM30 reps + 15 reps * 3KE, KF185Arterial compliance
Vascular conductance
+
~
Fry et al. (2010) [120] 7 men7020020% 1 RM30 reps + 15 reps * 3KE4-55D-dimer
Madarame et al. (2010) [174] 10 men25150–16030% 1 RM30 reps + 15 reps * 3LP?5PTF
TAT
D-dimer
FDP
~
~
~
~
Nakajima et al. (2007) [175] 6 men3216030% 1 RM30 reps + 15 reps * 3LP?5D-dimer
FDP
Fibrinogen
~
~
~
Takano et al. (2005) [116] 11 men34160–18020% 1 RM30 reps * 3 until exhaustionKE?3.3VEGF+

RM: repetition maximum; KE: knee extension; KF: knee flexion; LP: leg press; FMD: flow mediate dilation; SV: stroke volume; PP: pulse pressure; PTF: prothrombin fragment 1 + 2; TAT: thrombin antithrombin complex; FDP: fibrinogen degaradation product; VEGF: vascular endothelial growth factor. +: positive effect, −: negative effect, : no effect.