Blood Flow Restricted Exercise and Vascular Function

Table 2

Chronic effects of blood flow restricted training on vascular function and related biomarkers.

Author & year	Subjects	Age; (yrs)	Applied cuff; pressure; (mmHg)	Intensity or time	Reps, sets,; or time	Exercise; modality	Intervention; period	Occlusion; time; (min)	Cuff; width; (cm)	Outcome	Effect
Credeur et al. (2010) [140]	5 men; 7 women	22	80	60% 1 RM	15 reps/min, 20 min	HG	3 days/wk; 3 wk	20	?	FMD	−
Hunt et al. (2012) [141]	9 men	26	80	40% 1 RM	20 reps/min; until exhaustion	HG	3 days/wk; 4 wk	8.5	13	FMD; Diameter	~; +
Clark et al. (2011) [128]	8 men; 1 women	24	SBP * 1.3	30% 1 RM	8–12 reps/set,; Total 30–50 reps	KE	3 days/wk; 3 wk	?	6	PWV, ABI; D-dimer, PT; Fibrinogen	~,~; ~,~; ~
Fahs et al. (2012) [129]	10 men	21	160–200	20% 1 RM	30 reps +15 reps * 3 set	KE, KF	3 days/wk; 6 wk	12	5	Arterial compliance; Vascular conductance	~; ~
Kim et al. (2009) [127]	10 men	18–35	SBP * 1.2 * 1.2	20% 1 RM	10 reps * 2	KE, KF, LP	3 days/wk; 3 wk	<15	5	Arterial compliance	~
Ozaki et al. (2011) [134]	3 men; 10 women	66	140–200	45% HRR	20 min	walking	4 days/wk 10 wk	20	5	Arterial compliance	+
Ozaki et al. (2012) [130]	10 men	22–32	160	30% 1 RM	30 reps + 15 reps * 3 set	BeP	3 days/wk; 6 wk	?	3	Arterial compliance	~
Patterson and Ferguson (2010) [119]	8 men; 8 women	23; 22	110	25%, 50% 1 RM	20 reps/min * 3 sets	PF	3 days/wk 4 wk	5–8	?	Post-occlusive blood flow	+
Evans et al. (2010) [138]	9 men	20	150	Own BW	50 reps * 4	CR	3 days/wk 4 wk	?	?	Microvascular filtration capacity	+

SBP: systolic blood pressure; HRR: heart rate reserve; BW: body weight; HG: hand grip; PF: planter flexion; CR: calf raise; BeP: Bench press; PWV: pulse wave velocity; ABI: ankle-brachial blood pressure index. PT: prothrombin time; +: positive effect; −: negative effect; ∼: no effect.