Research Article

A Diet Enriched in Docosahexanoic Acid Exacerbates Brain Parenchymal Extravasation of Apo B Lipoproteins Induced by Chronic Ingestion of Saturated Fats

Figure 3

Effect of dietary fatty acids on plasma S100β concentration in C57BL/6J mice. The brain abundant protein S100β was measured in plasma as a surrogate marker of BBB leakage. High plasma S100β concentration in SFA-fed mice correlate with significant BBB dysfunction. In comparison to SFA 5 m group, plasma S100β was significantly increased in mice switched to the DHA diet (+DHA 2 m). The bars represent mean plasma concentration (pg/mL) and standard error of mean, where considered statistically significant (* one-way ANOVA).
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