A Diet Enriched in Docosahexanoic Acid Exacerbates Brain Parenchymal Extravasation of Apo B Lipoproteins Induced by Chronic Ingestion of Saturated Fats

Table 2

Effects of various feeding regimens on plasma lipids in wild-type (C57BL/6J) mice.

	SFA 5 m	+LF 2 m	+DHA 2 m
TG (mM)	0.39 ± 0.04	0.54 ± 0.03*	0.43 ± 0.04
TC (mM)	1.45 ± 0.23	1.69 ± 0.17	3.11 ± 0.12**
NEFA (mEq/L)	0.42 ± 0.03	0.45 ± 0.03	0.53 ± 0.05
Body weight
Final	25.65 ± 0.64	23.72 ± 0.96	20.21 ± 0.50**
Weight gain	8.41 ± 0.51	5.7 ± 1.12	3.3 ± 0.51**

Plasma total cholesterol (TC), triglycerides (TGs), and non-esterified fatty acids (NEFAs) were measured at the end of the feeding regimen in mice fed saturated fats (SFA 5 m) and SFA-fed mice switched to an LF (+LF 2 m) and DHA diet (+DHA 2 m). Final body weight and weight gain were also calculated. Data represented as mean ± standard error of mean. Means were compared with one-way ANOVA, where 𝑃<0.05 considered statistically significant (*).