Research Article

Lipofundin-Induced Hyperlipidemia Promotes Oxidative Stress and Atherosclerotic Lesions in New Zealand White Rabbits

Figure 1

Histopathological analysis of rabbit’s aortic tree. Eosin/hematoxylin staining reveals a normal morphology of aortas in control animals (a) and (c), while aortas of Lipofundin group show an intimal thickening, characterized by a vascular tissue architecture distortion and large extracellular spaces, probably filled with lipids (asterisks) (b) and (d). Arrow head: endothelial cells. Magnification 10× (a) and (b) and 40× (c) and (d). Scale bar, 20 μm.
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(a)
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(b)
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(c)
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(d)