Evaluation of Serum Biomarkers for Patients at Increased Risk of Stroke

Table 2

Levels of various clinical factors in blood serum of study subjects.

	Asym/stable	Asym/unstable	Sym/stable	Sym/unstable	𝑃 value**
	𝑛=25 of 110	𝑛=36 of 110	𝑛=13 of 110	𝑛=36 of 110
MMP-1 [ng/μL]	2.4±1.8	4.4±3.8	4.1±2.8	3.9±2.7	0.047
MMP-2 [ng/μL]	257±81	261±91	237±62	269±81	0.672
MMP-3 [ng/μL]	14.1±5.5	14.8±8.7	14.6±4.1	13.4±4.7	0.279
MMP-7 [ng/μL]	7.1±3.2	10.1±4.7	11.6±5.2	10.7±4.1	0.005
MMP-8 [ng/μL]	11.3±9.1	11.2±11.5	10.2±6.5	17.1±19.5	0.212
MMP-9 [ng/μL]	192±65	178±74	210±66	231±80	0.028
TIMP-1 [ng/μL]	139±41	161±70	167±47	182±59	0.044
TIMP-2 [ng/μL]	65.0±22.2	69.0±29.1	61.1±29.6	74.5±41.7	0.552
TNF-α [pg/μL]	2.5±0.8	3.2±1.2	2.3±1.4	3.3±1.5	0.134
IL-1𝛽 [pg/μL]	1.1±1.4	2.1±2.7	1.8±1.6	2.5±4.1	0.523
IL-6 [pg/μL]	2.2±1.2	3.3±1.9	2.8±1.1	3.9±2.8	0.397
IL-8 [pg/μL]	6.5±1.4	6.1±2.7	5.2±2.7	6.8±5.3	0.482
IL-10 [pg/μL]	1.4±0.9	1.8±0.7	1.6±1.1	3.0±2.7	0.234
IL-12 [pg/μL]	1.1±0.6	1.9±1.7	2.1±1.4	2.8±2.8	0.683
hsCRP [mg/dL]	1.1±1.2	1.2±0.7	2.3±2.8	2.1±1.6	0.060
Fibrinogen [mg/dL]	345±94	371±122	382±65	361±83	0.790
Leukocytes [mg/dL]	7.1±1.4	7.5±1.9	8.1±1.4	7.1±2.0	0.334

**One-way ANOVA (analysis of variance) was used.