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International Journal of Vascular Medicine
Volume 2012 (2012), Article ID 968761, 7 pages
Benfotiamine Counteracts Smoking-Induced Vascular Dysfunction in Healthy Smokers
1Diabetes Center, Heart and Diabetes Center NRW Bad Oeynhausen, Ruhr University of Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
2Profil Institute for Metabolic Research, Hellersbergstrasse 9, 41460 Neuss, Germany
3Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center NRW, Bad Oeynhausen, Ruhr University of Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
4Center for Diabetes, Nutrition and Metabolic Diseases, “Iuliu Hatieganu” University, Str. Clinicilor nr. 2, 400006 Cluj-Napoca, Romania
Received 13 February 2012; Revised 22 August 2012; Accepted 5 September 2012
Academic Editor: Tomoki Hashimoto
Copyright © 2012 Alin Stirban et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- M. Ezzati, S. J. Henley, M. J. Thun, and A. D. Lopez, “Role of smoking in global and regional cardiovascular mortality,” Circulation, vol. 112, no. 4, pp. 489–497, 2005.
- O. T. Raitakari, M. R. Adams, R. J. McCredie, K. A. Griffiths, R. Stocker, and D. S. Celermajer, “Oral vitamin C and endothelial function in smokers: short-term improvement, but no sustained beneficial effect,” Journal of the American College of Cardiology, vol. 35, no. 6, pp. 1616–1621, 2000.
- T. Neunteufl, U. Priglinger, S. Heher et al., “Effects of vitamin E on chronic and acute endothelial dysfunction in smokers,” Journal of the American College of Cardiology, vol. 35, no. 2, pp. 277–283, 2000.
- C. Vlachopoulos, D. Tsekoura, N. Alexopoulos, D. Panagiotakos, K. Aznaouridis, and C. Stefanadis, “Type 5 phosphodiesterase inhibition by sildenafil abrogates acute smoking-induced endothelial dysfunction,” American Journal of Hypertension, vol. 17, no. 11, pp. 1040–1044, 2004.
- D. S. Celermajer, K. E. Sorensen, D. Georgakopoulos et al., “Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults,” Circulation, vol. 88, no. 5, pp. 2149–2155, 1993.
- T. Kato, T. Inoue, T. Morooka, N. Yoshimoto, and K. Node, “Short-term passive smoking causes endothelial dysfunction via oxidative stress in nonsmokers,” Canadian Journal of Physiology and Pharmacology, vol. 84, no. 5, pp. 523–529, 2006.
- H. Van Der Vaart, D. S. Postma, W. Timens, and N. H. T. Ten Hacken, “Acute effects of cigarette smoke on inflammation and oxidative stress: a review,” Thorax, vol. 59, no. 8, pp. 713–721, 2004.
- D. M. Burns, “Cigarettes and cigarette smoking,” Clinics in Chest Medicine, vol. 12, no. 4, pp. 631–642, 1991.
- C. Cerami, H. Founds, I. Nicholl et al., “Tobacco smoke is a source of toxic reactive glycation products,” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 25, pp. 13915–13920, 1997.
- B. Guerci, A. Kearney-Schwartz, P. Böhme, F. Zannad, and P. Drouin, “Endothelial dysfunction and type 2 diabetes: part 1: physiology and methods for exploring the endothelial function,” Diabetes and Metabolism, vol. 27, no. 4, pp. 425–434, 2001.
- O. T. Raitakari, M. R. Adams, R. J. McCredie, K. A. Griffiths, and D. S. Celermajer, “Arterial endothelial dysfunction related to passive smoking is potentially reversible in healthy young adults,” Annals of Internal Medicine, vol. 130, no. 7, pp. 578–581, 1999.
- M. Law and J. L. Tang, “An analysis of the effectiveness of interventions intended to help people stop smoking,” Archives of Internal Medicine, vol. 155, no. 18, pp. 1933–1941, 1995.
- G. Siasos, D. Tousoulis, C. Vlachopoulos et al., “Short-term treatment with L-arginine prevents the smoking-induced impairment of endothelial function and vascular elastic properties in young individuals,” International Journal of Cardiology, vol. 126, no. 3, pp. 394–399, 2008.
- H. A. Hadi, C. S. Carr, and J. Al Suwaidi, “Endothelial dysfunction: cardiovascular risk factors, therapy, and outcome,” Vascular Health and Risk Management, vol. 1, no. 3, pp. 183–198, 2005.
- K. H. Schreeb, S. Freudenthaler, S. V. Vormfelde, U. Gundert-Remy, and C. H. Gleiter, “Comparative bioavailability of two vitamin B1 preparations: benfotiamine and thiamine mononitrate,” European Journal of Clinical Pharmacology, vol. 52, no. 4, pp. 319–320, 1997.
- H. P. Hammes, X. Du, D. Edelstein et al., “Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy,” Nature Medicine, vol. 9, no. 3, pp. 294–299, 2003.
- P. J. Thornalley, “The potential role of thiamine (vitamin B1) in diabetic complications,” Current Diabetes Reviews, vol. 1, no. 3, pp. 287–298, 2005.
- U. Schmid, H. Stopper, A. Heidland, and N. Schupp, “Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro,” Diabetes/Metabolism Research and Reviews, vol. 24, no. 5, pp. 371–377, 2008.
- V. Marchetti, R. Menghini, S. Rizza et al., “Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling,” Diabetes, vol. 55, no. 8, pp. 2231–2237, 2006.
- M. Kruse, D. Navarro, P. Desjardins, and R. F. Butterworth, “Increased brain endothelial nitric oxide synthase expression in thiamine deficiency: relationship to selective vulnerability,” Neurochemistry International, vol. 45, no. 1, pp. 49–56, 2004.
- V. L. Raghavendra Rao, D. D. Mousseau, and R. F. Butterworth, “Nitric oxide synthase activities are selectively decreased in vulnerable brain regions in thiamine deficiency,” Neuroscience Letters, vol. 208, no. 1, pp. 17–20, 1996.
- M. Shoeb and K. V. Ramana, “Anti-inflammatory effects of benfotiamine are mediated through the regulation of the arachidonic acid pathway in macrophages,” Free Radical Biology and Medicine, vol. 52, no. 1, pp. 182–190, 2012.
- P. Balakumar, R. Sharma, and M. Singh, “Benfotiamine attenuates nicotine and uric acid-induced vascular endothelial dysfunction in the rat,” Pharmacological Research, vol. 58, no. 5-6, pp. 356–363, 2008.
- S. Arora, A. Lidor, C. J. Abularrage et al., “Thiamine (vitamin B1) improves endothelium-dependent vasodilatation in the presence of hyperglycemia,” Annals of Vascular Surgery, vol. 20, no. 5, pp. 653–658, 2006.
- A. Stirban, M. Negrean, B. Stratmann et al., “Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes,” Diabetes Care, vol. 29, no. 9, pp. 2064–2071, 2006.
- D. S. Celermajer, K. E. Sorensen, V. M. Gooch et al., “Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis,” The Lancet, vol. 340, no. 8828, pp. 1111–1115, 1992.
- S. Guthikonda, C. A. Sinkey, and W. G. Haynes, “What is the most appropriate methodology for detection of conduit artery endothelial dysfunction?” Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 27, no. 5, pp. 1172–1176, 2007.
- M. C. Corretti, T. J. Anderson, E. J. Benjamin et al., “Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the international brachial artery reactivity task force,” Journal of the American College of Cardiology, vol. 39, no. 2, pp. 257–265, 2002.
- M. Hashimoto, M. Akishita, M. Eto et al., “Modulation of endothelium-dependent flow-mediated dilatation of the brachial artery by sex and menstrual cycle,” Circulation, vol. 92, no. 12, pp. 3431–3435, 1995.
- A. S. Postadzhiyan, A. V. Tzontcheva, I. Kehayov, and B. Finkov, “Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and their association with clinical outcome, troponin T and C-reactive protein in patients with acute coronary syndromes,” Clinical Biochemistry, vol. 41, no. 3, pp. 126–133, 2008.
- R. A. Kowluru, “Diabetes-induced elevations in retinal oxidative stress, protein kinase C and nitric oxide are interrelated,” Acta Diabetologica, vol. 38, no. 4, pp. 179–185, 2001.
- M. Y. Rhee, S. H. Na, Y. K. Kim, M. M. Lee, and H. Y. Kim, “Acute effects of cigarette smoking on arterial stiffness and blood pressure in male smokers with hypertension,” American Journal of Hypertension, vol. 20, no. 6, pp. 637–641, 2007.
- B. Balint, L. E. Donnelly, T. Hanazawa, S. A. Kharitonov, and P. J. Barnes, “Increased nitric oxide metabolites in exhaled breath condensate after exposure to tobacco smoke,” Thorax, vol. 56, no. 6, pp. 456–461, 2001.
- E. Berrone, E. Beltramo, C. Solimine, A. U. Ape, and M. Porta, “Regulation of intracellular glucose and polyol pathway by thiamine and benfotiamine in vascular cells cultured in high glucose,” Journal of Biological Chemistry, vol. 281, no. 14, pp. 9307–9313, 2006.
- F. Pomero, A. Molinar Min, M. La Selva, A. Allione, G. M. Molinatti, and M. Porta, “Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose,” Acta Diabetologica, vol. 38, no. 3, pp. 135–138, 2001.
- R. Avena, S. Arora, B. J. Carmody, K. Cosby, and A. N. Sidawy, “Thiamine (vitamin B1) protects against glucose- and insulin-mediated proliferation of human infragenicular arterial smooth muscle cells,” Annals of Vascular Surgery, vol. 14, no. 1, pp. 37–43, 2000.
- A. Stirban, M. Negrean, B. Stratmann et al., “Adiponectin decreases postprandially following a heat-processed meal in individuals with type 2 diabetes: an effect prevented by benfotiamine and cooking method,” Diabetes Care, vol. 30, no. 10, pp. 2514–2516, 2007.
- Y. Kohda, H. Shirakawa, K. Yamane et al., “Prevention of incipient diabetic cardiomyopathy by high-dose thiamine,” Journal of Toxicological Sciences, vol. 33, no. 4, pp. 459–472, 2008.
- I. Shimon, S. Almog, Z. Vered et al., “Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy,” American Journal of Medicine, vol. 98, no. 5, pp. 485–490, 1995.
- P. J. Thornalley, R. Babaei-Jadidi, H. Al Ali et al., “High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease,” Diabetologia, vol. 50, no. 10, pp. 2164–2170, 2007.
- A. R. Dyer, P. Elliott, J. Stamler, Q. Chan, H. Ueshima, and B. F. Zhou, “Dietary intake in male and female smokers, ex-smokers, and never smokers: the INTERMAP Study,” Journal of Human Hypertension, vol. 17, no. 9, pp. 641–654, 2003.
- T. Motoyama, H. Kawano, K. Kugiyama et al., “Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: effect of vitamin C,” American Journal of Physiology, vol. 273, no. 4, pp. H1644–H1650, 1997.
- N. Bonello and R. J. Norman, “Soluble adhesion molecules in serum throughout the menstrual cycle,” Human Reproduction, vol. 17, no. 9, pp. 2272–2278, 2002.
- C. Papamichael, E. Karatzis, K. Karatzi et al., “Red wine's antioxidants counteract acute endothelial dysfunction caused by cigarette smoking in healthy nonsmokers,” American Heart Journal, vol. 147, no. 2, p. E5, 2004.