Benfotiamine Counteracts Smoking-Induced Vascular Dysfunction in Healthy Smokers

Table 1

Clinical parameters, arterial diameter of the brachial artery and laboratory parameters during the 2 study days.

	Without benfotiamine		With benfotiamine
	Before smoking	After smoking	Before smoking	After smoking
Systolic blood pressure (mmHg)	121±3	124±3	117±2	121±2^∗
Diastolic blood pressure (mmHg)	75±2	78±2^∗	75±2	77±2
Heart rate (beats/min)	69±2	75±2^∗	68±2	74±2^∗
Brachial artery diameter at baseline (mm)	3.39±0.95	3.41±0.10	3.52±0.10	3.50±0.12
Postischemic diameter (mm)	3.64±0.09	3.54±0.09^∗	3.76±0.09	3.67±0.11^∗
sVCAM (ng/mL)	468±24	488±25^∗	484±21	484±24
TBARS (nmol/mL)	7.4±0.3	7.5±0.3	7.4±0.5	7.8±0.5

^∗𝑃<0.05 after smoking versus before smoking.