Etanercept Suppresses Arteritis in a Murine Model of Kawasaki Disease: A Comparative Study Involving Different Biological Agents

Figure 4

Correlation between histological changes and plasma cytokine levels. Correlation between the total area of inflammation and cytokine levels at 4 weeks. Relationship between the degree of vasculitis, indicated by the total area of inflammation (mm²), and plasma levels (pg/mL) of TNF-α (a), IL-13 (b), and IL-6 (c).

(a)  Area of inflammation versus TNF-𝛼

(b) Area of inflammation versus IL-13

(c) Area of inflammation versus IL-6