Clinical Study

Thrombophilic Genetic Factors PAI-1, MTHFRC677T, V Leiden 506Q, and Prothrombin 20210A in Noncirrhotic Portal Vein Thrombosis and Budd-Chiari Syndrome in a Caucasian Population

Table 3

Thrombophilic genetic factors (THRGFs), PAI-1 4G-4G, MTHFR677TT, V Leiden 506Q, and Prothrombin 20210A, in patients with abdominal thrombosis with myeloproliferative neoplasm (MPN), recent abdominal surgery (RAS), oral contraception or pregnancy (OCP), chronic disease (CD), abdominal acute disease (AAD), and it a single disease or clinical status associated (NODCSA).

ā€‰MPN (%)RAS (%)OCP (%)AAD (%)CD (%)NODCSA (%)Total

Number of patients37 (100)12 (100)10 (100)7 (100)9 (100)10 (100)85 (100)
PAI-1 4G-4G18 (48.6)7 (58.3)6 (60)4 (57.1)6 (66.6)6 (60.0)47 (55.3)
MTHFR677TT 8 (21.6)2 (16.6)3 (30)2 (28.5)3 (33.3)6 (60.0)24 (28.2)
V Leiden 506Q6 (16.2)1 (8.3)3 (30)0 (0)0 (0)3 (30.0)13 (15.3)
Prothrombin 20210A 2 (5.4)0 (0)0 (0)1 (14.3)0 (0)2 (20.0)5 (5.8)
>1 THRGF5 (13.5)1 (8.3)2 (20.0)0 (0)1 (11.1)6 (60.0)15 (17.6)
At least 1 THRGF28 (75.7)10 (83.3)10 (100)7 (100)9 (100)10 (100)73 (87.1)