| | Risk scores | Country | Population | Risk factors | Outcomes |
| | Framingham [26] 1976 | USA | Population cohort | Age, sex, smoking, SBP, total cholesterol, random blood sugar and urinary blood glucose, ECG-LVH | Deaths from CHD and other fatal CVD, MI, ischaemic stroke, haemorrhagic stroke, angina pectoris, PAD, hypertensive CCF |
| | Framingham [27] 1991 | USA | Population cohort (original + offspring) | Age, sex, smoking, SBP, DBP, TC, HDL, RBS, (offspring FBS) ECG-LVH | Death from CHD, MI, angina pectoris |
| | Framingham [57] 1998 | USA | Population cohort (original + offspring) | Age, sex, smoking, SBP, DBP, TC or LDL, RBS, (offspring FBS) | Death from CHD, MI, angina pectoris |
| |
Framingham [28] 2008 | USA | Population cohort (original + offspring) | Lab based-Age, sex, smoking, SBP, TC, HDL, FBS, antihypertensive | Deaths from CHD and other fatal CVD, MI, ischaemic stroke, haemorrhagic stroke, TIA, angina pectoris, PAD, hypertensive CCF | | Non-lab-Age, sex, smoking, SBP, FBS, antihypertensive, BMI |
| | UKPDS [40] 2001 | UK diabetes prevention trial | Population cohort | Age at diagnosis of diabetes, smoking, SBP, TC/HDL, HbA1c, ethnicity | Hard CHD |
| |
PROCAM [29] 2007 | Germany | Occupational cohort | CHD-Age, sex, smoking, SBP, LDL, HDL, TG, FBS, family history | Deaths from CHD and MI | | Stroke-Age, sex, smoking, SBP, FBS | Ischemic stroke, TIA |
| | SCORE [38] 2003 | Europe | Pooled dataset of cohort studies | Age, sex, smoking, BP, TC or TC : HDL | Deaths from CHD and other fatal CVD, fatal MI, fatal ischemic score, fatal PAD, fatal hypertensive CCF |
| | ARIC [30] 2003 | USA | Population cohort | Age, sex, smoking, SBP, TC, HDL, FBS, antihypertensive, ethnicity | Death form CHD, MI, revascularisation intervention |
| | Dubbo equation [58] 2003 | Australia | Second Australian
national blood pressure study | Age, sex, smoking, SBP, antihypertensive medication, TC, HDL, diabetes | CVD |
| | Progetto coure [59] 2004 | Italy | Pooled dataset of cohort studies | Age, sex, smoking, SBP, TC, HDL, FBS, antihypertensive | Deaths from CHD and other fatal CVD, MI, ischemic stroke, haemorrhagic stroke, revascularisation intervention |
| | DECODE [60] 2005 | Sweden | National diabetes registry | Age, state of glucose tolerance, FBS, smoking, SBP, TC, HDL, BMI, HR | Fatal CVD and first incident CVD |
| | Riskard [61] 2005 | Italy | Population cohort | Age, sex, smoking, mean BP, HDL-C, non-HDL-C, diabetes, BMI, heart rate | CVD, CHD and stroke |
| |
Zhang et al. [62] 2005 | China | Occupational cohort | CHD-Age, smoking, SBP, TC, BMI | CHD | | Ischemic stroke-age, smoking, SBP, TC | Ischaemic stroke | | Haemorrhagic stroke-age, SBP, DBP, TC | Haemorrhagic stroke |
| | Strong Heart Study [36] 2006 | USA | Population cohort-American Indian | Age, sex, smoking, SBP, TC or LDL, HDL, FBS, antihypertensive, albuminuria | Death from CHD, MI, angina pectoris, revascularisation interventions |
| | USA-PRC [37] 2006 | China | Population cohort | Age, sex, smoking, SBP, TC, FBS, BMI | Deaths from CHD and other fatal CVD, MI, ischemic stroke |
| | NIPPON data80 [63] 2006 | Japan | Population cohort | Age, sex, smoking, SBP, TC, blood glucose | Fatal CHD, fatal stroke, and fatal CVD |
| | ASSIGN [35] 2007 | UK | Population cohort | Age, sex, smoking, SBP, TC, HDL, diabetes, family history, socioeconomic status | Deaths from CHD and other fatal CVD, MI, revascularisation intervention, hypertensive CCF and; admitted for MI, ischemic stroke, haemorrhagic stroke, TIA or angina pectoris |
| | Reynolds women [33] 2007 | USA | Women’s health Study trial subjects | Age, smoking, self-reported BP, TC, HDL, HbA1c (if diabetic), family history, hs-CRP | Deaths from CHD and other fatal CVD, MI, ischaemic stroke, revascularisation intervention |
| | Reynolds men [34] 2008 | USA | Physician health study trial subjects | Age, smoking, Self-reported BP, TC, HDL, diabetics excluded in baseline, family history, hs-CRP | Deaths from CHD and other fatal CVD, MI, stroke, revascularisation interventions |
| | Personal heart [39] men 2007 | USA | Population cohort | Men age, smoking, previous diagnosis of HTN, previous diagnosis of hypercholesterolemia, previous diagnosis of diabetes, family history, physical activity
Women age, smoking, previous diagnosis of hypertension, previous diagnosis of hypercholesterolemia, previous diagnosis of diabetes, BMI | Death from CHD, MI, revascularisation intervention |
| | QRISK [31] 2007 | UK | Electronic medical database | Age, sex, smoking, SBP, TC : HDL, diabetics excluded in baseline, antihypertensives, BMI, family history, townsend | Deaths from CHD and other fatal CVD, MI, stroke, TIA, angina pectoris |
| | QRISK2 [32] 2008 | UK | Electronic medical database | Age, sex, smoking, SBP, TC : HDL, FBS, antihypertensive, BMI, ethnicity, family history, townsend, rheumatoid arthritis, chronic renal disease, atrial fibrillation | Deaths from CHD and other fatal CVD, MI, ischaemic stroke, TIA, angina pectoris |
| | NHEFS [2] 2008 | USA | Population cohort | Age, sex, smoking, SBP, previous diagnosis of diabetes, BMI | Deaths from CHD and other fatal CVD, MI, stroke, revascularisation interventions, Hypertensive CCF |
| | IHMRS [41] 2011 | 52 countries | Cases of MI, age (±5 years), and sex-matched controls | Age, apolipoprotein B : A1 ratio, smoking, second-hand smoke, diabetes, high blood pressure | Cases of acute MI |
|
|
