Chronic NaHS Treatment Is Vasoprotective in High-Fat-Fed ApoE^−/− Mice

Table 1

Effect of chronic treatment with NaHS or PPG on plasma lipid profile.

Group	𝑛	Total cholesterol (mM)	HDL (mM)	LDL (mM)	Trigylceride (mM)
WT control	3–5	3.1±0.03	1.3±0.2	0.2±0.02	2.2±0.2
Fat-fed ApoE−/−
Untreated	4–6	32.1±5.9^∗∗∗	2.5±0.4	6.5±1.0^∗∗∗	2.0±0.4
NaHS (10 𝜇mol/kg/day)	4–7	32.3±3.4^∗∗∗	2.4±0.2	7.9±1.0^∗∗∗	1.9±0.3
NaHS (100 𝜇mol/kg/day)	6-7	37.7±2.2^∗∗∗	1.6±0.1	6.9±0.4^∗∗∗	1.9±0.2
PPG 30 mg/kg/day	3–6	33.1±3.2^∗∗∗	2.4±0.5	8.3±1.1^∗∗∗	2.4±0.3

*** 𝑃<0.0001, ANOVA, C57 compared with untreated fat-fed ApoE−/−.