Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model

Table 1

Modified limb-placing test (MLPT).

Group treatment	Ambulation	Placing/stepping reflex	MDI
Normal	0	0	0
SAH	1.28 ± 0.17	1.50 ± 0.13	2.78 ± 0.30
SAH + vehicle	1.28 ± 0.11	1.58 ± 0.21	2.86 ± 0.32
SAH + purpurogallin
100 ug/kg/day	0.91 ± 0. 60	1.54 ± 0.25	2.45 ± 0.85
200 ug/kg/day	0. 82 ± 0.25	0.83 ± 0.43^*	1.65 ± 0.68
400 ug/kg/day	0.56 ± 0.22^*	0.65 ± 0.20^*	1.21 ± 0.42^*

Results are expressed as the means ± SEM, = 9; versus SAH condition by Mann-Whitney test.