Research Article
Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model
Table 1
Modified limb-placing test (MLPT).
| Group treatment | Ambulation | Placing/stepping reflex | MDI |
| Normal | 0 | 0 | 0 | SAH | 1.28 ± 0.17 | 1.50 ± 0.13 | 2.78 ± 0.30 | SAH + vehicle | 1.28 ± 0.11 | 1.58 ± 0.21 | 2.86 ± 0.32 | SAH + purpurogallin | | | | 100 ug/kg/day | 0.91 ± 0. 60 | 1.54 ± 0.25 | 2.45 ± 0.85 | 200 ug/kg/day | 0. 82 ± 0.25 | 0.83 ± 0.43* | 1.65 ± 0.68 | 400 ug/kg/day | 0.56 ± 0.22* | 0.65 ± 0.20* | 1.21 ± 0.42* |
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Results are expressed as the means ± SEM, = 9; versus SAH condition by Mann-Whitney test.
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