The Human Vaginal Bacterial Biota and Bacterial Vaginosis
Figure 7
Vaginal biopsy from a
subject with BV. A Gardnerella vaginalis biofilm (yellow) is detected at the edge of
the vaginal epithelium (bottom) by fluorescence in situ hybridization
(FISH). The yellow color is the result
of using a combination of probes targeting G.
vaginalis (Red), all bacteria (Eub338, green), and ,6-diamidine-2-phenylindole, dihydrochloride
(DAPI, blue) which stains DNA. Note
human cell nuclei in blue. The image on
the right shows a vaginal epithelial cell with a cluster of G. vaginalis breaking off the epithelium
and likely forming a clue cell.