Neuroinvasion in Prion Diseases: The Roles of Ascending Neural Infection and Blood Dissemination
Figure 5
Magnitude of PrPd accumulation in LRS tissues of sheep as part of the blood transfusion experiment [95]. BSE donor sheep showed the highest levels of PrPd accumulation in palatine tonsil and mesenteric lymph node (MsLN) but the lowest in the spleen. In contrast, the spleen in BSE-transfused sheep showed significant higher magnitudes of PrPd. Graphic representation including scrapie data has been modified from [96, 97].
