Leprosy: An Overview of Pathophysiology

Table 1

Clinical features of leprosy.

Characteristics	Tuberculoid	Borderline tuberculoid	Midborderline	Borderline lepromatous	Lepromatous leprosy
Number of lesions	Single or upto 3	A Few (up to 10)	Several (10–30)	Numerous, asymmetrical (>30)	Innumerable, symmetrical
Size	Variable,; usually large	Variable, some are large	Variable	Small, some; can be large	Small
Surface changes	Hypopigmented	Dry, scaly, look bright, and infiltrated	Dull or slightly shiny	Shiny	Shiny
Sensations	Absent	Markedly diminished	Moderately diminished	Slightly diminished	Minimally diminished
Hair growth	Nil	Markedly diminished	Moderately diminished	Slightly diminished	Not affected initially
Skin smear	Negative	Negative or 1+	1–3+	3–5+	Plenty, including globi (6+)
Lepromin test	Strongly positive	Weakly positive	Negative	Negative	Negative