Interdisciplinary Perspectives on Infectious Diseases / 2012 / Article / Tab 2 / Clinical Study
Natural History and Factors Associated with Early and Delayed Mortality in HIV-Infected Patients Treated of Tuberculosis under Directly Observed Treatment Short-Course Strategy: A Prospective Cohort Study in India Table 2 Cox regression analysis of factors associated with death during the first three months of anti-tuberculosis treatment.
Overall Males Females HR (95% CI)
valueHR (95% CI)
valueHR (95% CI)
valueAge (years) <35 1 1 1 >35 1.37 (1.06–1.77) 0.017 1.24 (0.91–1.68) 0.179 1.83 (1.14–2.94) 0.013 Literacy Yes 1 1 1 No 1.08 (0.82–1.41) 0.593 0.98 (0.72–1.34) 0.917 1.5 (0.75–2.98) 0.248 Homeless No 1 1 1 Yes 2.6 (1.65–4.08) <0.001 2.57 (1.34–4.93) 0.004 3.29 (1.69–6.42) <0.001 Community ST/SC 1.41 (1.08–1.84) 0.011 1.58 (1.15–2.16) 0.005 1.06 (0.64–1.75) 0.822 OC/BC 1 1 1 CD4+ lymphocyte count* <100 2.22 (1.4–3.52) 0.001 1.74 (0.99–3.04) 0.053 3.09 (1.35–7.09) 0.008 100–250 1.52 (0.95–2.42) 0.08 1.2 (0.69–2.11) 0.521 2.14 (0.92–4.95) 0.077 >250 1 1 1 Previous ATT No (category I) 1 1 1 Yes (category II) 1.2 (0.88–1.63) 0.251 1.15 (0.8–1.65) 0.452 1.32 (0.73–2.38) 0.364 Organ involved Meningitis 1.82 (1.37–2.43) <0.001 2.02 (1.45–2.83) <0.001 1.21 (0.67–2.21) 0.526 Disseminated 1.43 (0.87–2.38) 0.162 1.45 (0.82–2.55) 0.197 1.5 (0.46–4.84) 0.5 Others 1 1 1 ART before ATT No 1 1 1 Yes 1.32 (1.01–1.73) 0.043 1.28 (0.92–1.77) 0.138 1.46 (0.89–2.39) 0.135 Gender Male 1.12 (0.83–1.5) 0.456 Female 1
AFB: acid fast bacilli; ART: antiretroviral therapy; ATT: anti-tuberculosis treatment; CI: confidence interval; HR: hazard ratio. *cells/mm3 .