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Interdisciplinary Perspectives on Infectious Diseases
Volume 2012 (2012), Article ID 585901, 4 pages
http://dx.doi.org/10.1155/2012/585901
Research Article

The Use of Albuterol in Young Infants Hospitalized with Acute RSV Bronchiolitis

1Department of Pediatrics, Temple University School of Medicine, Philadelphia, PA 19140, USA
2Department of Pediatrics, Emory University, Atlanta, GA 30322, USA
3Department of Epidemiology and Biostatistics, Temple University School of Medicine, Philadelphia, PA 19140, USA

Received 2 May 2012; Revised 12 July 2012; Accepted 18 July 2012

Academic Editor: Mary E. Marquart

Copyright © 2012 Michael T. Del Vecchio et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To evaluate the effects of albuterol use in young infants admitted with respiratory syncytial virus (RSV) bronchiolitis with regards to length of time on supplemental oxygen and length of stay (LOS). To consider the possibility that albuterol use may increase the need for supplemental oxygen and increase LOS. Design, Setting, and Participants. Full-term infants between the ages of 11 days and 90 days ( 𝑁 = 3 1 6 ) were included in this retrospective study. Infants included were hospitalized with a diagnosis of RSV bronchiolitis at a university-affiliated children’s hospital. Results. In 4 of 5 severity groups, patients who received albuterol required more time on supplemental oxygen and had longer LOS. The differences only reached statistical significance in one of the severity groups in regards to LOS. Conclusions. The use of albuterol does not appear to be useful in the treatment of young infants with RSV bronchiolitis and may actually be harmful, in regards to increased supplemental oxygen need.