A 5-Year Retrospective Review of Fungal Keratitis at Hospital Universiti Sains Malaysia

Table 2

Treatment modalities and outcome according to each fungal isolates.

Type of fungal (n)	Vision at presentation					Vision posttreatment
	<6/18	6/18–1/60	CF-PL	NPL	Treatment	less than 6/18	6/18–1/60	CF-PL	NPL
Hyaline
Fusarium sp. (19)	6	4	9		G. Natamycin if available, G. Amphotericin. B, Oral & Gut Fluconazole. 5 PK, 1 evisceration	10	3	4	2
Aspergillus sp. (4)		1	3		G. Natamycin, Voriconazole, Amphotericin B; Oral Fluconazole. 1 scleral patch, 2 PK			3	1
Scedosporium sp. (1)			1		Gutt Amphotericin B & Voriconazole. Oral Voriconazole.	1
Trichoderma sp. (1)	1				Gutt. Ciprofloxacin (Provisional diagnosis: marginal keratitis)	1
Epidermophyton sp. (1)	1				Gutt. Amphotericin B & Fluconazole. Oral Fluconazole.	1
Yeast
Candida albicans (2); (1 immunocompromised; patient with bilateral involvement)	1		1		Gutt Amphotericin B	1		1
Candida parapsilosis (2)		1	1		Gutt Amphotericin B		1	1
(infected cornea graft)					Repeat penetrating keratoplasty
Candida tropicalis (1)				1	Gutt Amphotericin B				1
(Ocular ischaemic syndrome)
Dermatiaceous
Curvularia sp. (2)	2				Gutt. Amphotericin B	2
Nonsporulating fungi (3)	1		2		Gutt. Amphotericin B	2	1
Unidentified hyaline (4)	1		3		All required systemic + topical treatment; Natamycin in one case. One required PK.	2		2
Unidentified yeast (1)			1		Gutt Amphotericin B		1

Abbreviations: CF: counting finger, PK: penetrating keratoplasty, NPL: no perception of light, PL: perception of light.