Clinical Study
A 5-Year Retrospective Review of Fungal Keratitis at Hospital Universiti Sains Malaysia
Table 2
Treatment modalities and outcome according to each fungal isolates.
| Type of fungal (n) | Vision at presentation | | Vision posttreatment | <6/18 | 6/18–1/60 | CF-PL | NPL |
Treatment | less than 6/18 | 6/18–1/60 | CF-PL | NPL |
| Hyaline | | | | | | | | | | Fusarium sp. (19) | 6 | 4 | 9 | | G. Natamycin if available, G. Amphotericin. B, Oral & Gut Fluconazole. 5 PK, 1 evisceration | 10 | 3 | 4 | 2 | Aspergillus sp. (4) | | 1 | 3 | | G. Natamycin, Voriconazole, Amphotericin B Oral Fluconazole. 1 scleral patch, 2 PK | | | 3 | 1 | Scedosporium sp. (1)
| | | 1 | | Gutt Amphotericin B & Voriconazole. Oral Voriconazole. | 1 | | | | Trichoderma sp. (1) | 1 | | | | Gutt. Ciprofloxacin (Provisional diagnosis: marginal keratitis) | 1 | | | | Epidermophyton sp. (1) | 1 | | | | Gutt. Amphotericin B & Fluconazole. Oral Fluconazole. | 1 | | | |
| Yeast | | | | | | | | | | Candida albicans (2) (1 immunocompromised patient with bilateral involvement) | 1 | | 1 | | Gutt Amphotericin B | 1 | | 1 | | Candida parapsilosis (2) | | 1 | 1 | | Gutt Amphotericin B | | 1 | 1 | | (infected cornea graft) | | | Repeat penetrating keratoplasty | | | | | Candida tropicalis (1) | | | | 1 | Gutt Amphotericin B | | | | 1 | (Ocular ischaemic syndrome) | | | | | | | |
| Dermatiaceous | | | | | | | | | | Curvularia sp. (2) | 2 | | | | Gutt. Amphotericin B | 2 | | | |
| Nonsporulating fungi (3) | 1 | | 2 | | Gutt. Amphotericin B | 2 | 1 | | |
| Unidentified hyaline (4) | 1 | | 3 | | All required systemic + topical treatment Natamycin in one case. One required PK. | 2 | | 2 | |
| Unidentified yeast (1) | | | 1 | | Gutt Amphotericin B | | 1 | | |
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Abbreviations: CF: counting finger, PK: penetrating keratoplasty, NPL: no perception of light, PL: perception of light.
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