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Reference/author journal | Case | HAART regimen | Injection (TCA) | Clinical presentation | Hydrocortisone replacement | Time to recovery |
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Yombi et al. Clin Rheumatol 2008 [5] | 54 yo woman | 3TC/DDI/lopinavir-ritonavir | 40 mg (knee) | IACS Hypertension SAI | 20 mg daily | 8 months |
56 yo man | D4T/AZT/indinavir-ritonavir | 40 mg (cervical) | IACS SAI | 10 mg daily | 4 months |
49 yo woman | 3TC/DDI/lopinavir-ritonavir | 40 mg (shoulder) | IACS SAI | None | 5 months |
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Ramanathan et al. [6] CID 2008 | 35 yo man | Tenofovir-emtricitabine/lopinavir-ritonavir | 60 mg and then 80 mg (L spine) | IACS Hypertension Esophageal reflux | — | 4 months |
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Danaher et al. [7] Orthopedics 2009 | 44 yo man | Ritonavir based regimen | 80 mg (hip) | HHS-ICU admission IACS SAI | Unknown | Unknown |
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Dort et al. [8] AIDS Research and Therapy 2009 | 41 yo man | Tenofovir-emtricitabine, atazanavir-ritonavir | 80 mg twice (epidural) | IACS Hypertension AVN hip (at 11 months) | None | 6 months |
42 yo woman | Tenofovir-emtricitabine, atazanavir-ritonavir | 40 mg (shoulder) | IACS | 30 mg daily (short) | 2 months |
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Levine et al. [9] J Am Acad Dermatol 2011 | 41 yo woman | Lamivudine, tenofovir, atazanavir-ritonavir | 60 mg IM (topical steroid unresponsive nonspecific dermatitis) | IACS SAI | None | 6 months |
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Albert et al. [10] Am J Med Sciences 2012 | 58 yo woman | Tenofovir-emtricitabine, fosamprenavir-ritonavir | Epidural dose is not mentioned | IACS SAI | None | 2 months |
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Grierson and Harrast [11] Am Acad PMR 2012 | 47 yo woman | Tenofovir-emtricitabine, atazanavir-ritonavir | 80 mg 3 occasions (epidural L spine) | “Lipodystrophy” DM Metabolic syndrome IACS SAI | 20 mg daily (extended taper) | “Several months” |
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Fessler et al. [12] Pain Physician 2012 | 42 yo man | Tenofovir-emtricitabine, atazanavir-ritonavir | 80 mg (lumbar epidural) | Hypertension Acne (on back) | None | 3 months |
47 yo woman | Abacavir, lamivudine, darunavir-ritonavir → changed to abacavir, lamivudine, unboosted fosamprenavir upon dx | 80 mg 2 occasions (lumbar epidural) Also used inhaled fluticasone/salmeterol inhaler for asthma for 5 days | Weight gain Emotional lability IACS Hypertension Oral candidiasis | None | 10 weeks (improved) |
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Maviki et al. [13] Skeletal Radiology 2013 | 39 yo woman | Tenofovir-emtricitabine, darunavir-ritonavir | 40 mg 2 occasions (right L5 nerve root) | IACS Oral candidiasis SAI | Hydrocortisone “maintenance” | 8 months |
47 yo man | Tenofovir-emtricitabine, lopinavir-ritonavir | 80 mg (subacromial, subdeltoid bursa) | IACS Hyperglycemia Weight gain SAI | Hydrocortisone “maintenance” | 6 months |
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Schwarze-Zander et al. [14] Infection 2013 | 35 yo woman | Tenofovir-emtricitabine, saquinavir-ritonavir → changed to tenofovir-emtricitabine with raltegravir | 6 times 20 mg weekly (L5-S1 periradicular) | IACS Hypokalemia SAI Steroid-induced myopathy Acute herpes zoster (4 week later) | Hydrocortisone 15 mg/daily-tapered at 8 months Comment: also needed potassium replacement for hypokalemia | 8 months |
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Hall et al. [15] Int J STD AIDS 2013 | 53 yo woman | Darunavir-ritonavir Raltegravir | 40 mg (left shoulder) | Hyperglycemia (worse than usual for her controlled DM) Hypertension (worse than prior) IACS Anxiety | None Comment: needed initiation of insulin for DM previously controlled by metformin | 3 months |
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Sadarangani et al. | 48 yo woman | Tenofovir-emtricitabine, atazanavir-ritonavir → changed to tenofovir-emtricitabine with raltegravir | 40 mg triamcinolone epidural injection and 20 mg triamcinolone injection into right trochanteric bursa | Severe esophagitis (erosive, as well as candida and HSV esophagitis) IACS Relative SAI Mood changes-anxiety Weight gain | None Comment: needed course of fluconazole and valacyclovir as well as extended course therapy with proton pump inhibitor for esophagitis | 3-4 months |
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