Admission Outcome and Antimicrobial Resistance Pattern of Bacterial Isolates among Neonates with Suspected Sepsis in Neonatal Intensive Care Unit at Dessie Comprehensive Specialized Hospital, Dessie, Northeastern Ethiopia

Table 3

Bivariable and multi-variable analysis of neonatal data in relation to neonates with suspected sepsis admitted in NICU at Dessie Comprehensive Specialized Hospital, Dessie, Northeastern Ethiopia, August 2017 to March 2018.

S.no.	Characteristics	Bi-variable analysis		Multivariable analysis
		Corollary (95% CI)	-value	AOR (95% CI)	-value
1	Age in days
	>3–28	2.56 (1.29–5.06)	0.007	2.15 (0.96–4.8)	0.062
	≤3	Ref		Ref
2	Gender
	Female	1.21 (0.67–2.17)	0.522
	Male	Ref
3	Birth weight in Gram
	<2500	1.05 (0.6–1.84)	0.866
	≥2500	Ref
4	Neonate gestational age (week)
	<37	1.03 (0.59–1.8)	0.928
	≥37	Ref
5	Birth aspexia
	No	0.36 (0.07–1.85)	0.223	0.28 (0.04–2.05)	0.211
	Yes	Ref		Ref
6	Neonatal temperature, °c
	35.5–37.5	Ref		Ref
	<35.5	0.92 (0.44–1.9)	0.820	0.26 (0.11–0.65)	0.004
	>37.5	0.27 (0.13–0.53)	0.000	0.82 (0.36–1.88)	0.637
7	Respiratory rate
	≥60	0.59 (0.34–1.05)	0.073	0.58 (0.29–1.16)	0.123
	40–60	Ref		Ref
8	Pulse rate
	>160	0.81(0.41–1.6)	0.545
	120–160	Ref
9	Lethargy
	No	0.78 (0.43–1.42)	0.424
	Yes	Ref
10	Cyanosis
	No	0.49 (0.11–2.24)	0.356
	Yes	Ref
11	Grunting
	No	2.88 (1.23–6.75)	0.015	2.14 (0.82–5.56)	0.119
	Yes	Ref		Ref
12	Chest in drawing
	No	0.998 (0.26–3.88)	0.998
	Yes	Ref
13	Respiratory distress
	No	0.87 (0.22–3.46)	0.841
	Yes	Ref
14	Feeding
	Normal	Ref	0.168	Ref	0.794
	Refusal	0.62 (0.31–1.23)		0.9 (0.39–2.04)
15	Umblicus
	Clean	Ref	0.002	Ref	0.01
	Septic	12.0 (2.48–58.1)		10.06 (1.75–57.8)
16	Clinical jaundice
	No	Ref	0.344
	Yes	1.66 (0.58–4.77)
17	Indwelling medical devices
	No	Ref	0.037	Ref	0.022
	Yes	1.83 (1.04–3.24)		2.2 (1.12–4.32)
18	Vomiting
	No	Ref	0.119	Ref	0.350
	Yes	1.79 (0.86–3.73)		1.51 (0.64–3.59)
19	Diarrhea
	No	Ref	0.091	Ref	0.574
	Yes	3.72 (0.81–17.11)		1.66 (0.29–9.58)
20	APGAR score fifth
	≥7	Ref	0.053	Ref	0.703
	<7	2.22 (0.99–4.99)		1.99 (0.56–68.04)
21	APGAR score first
	≥7	Ref	0.073	Ref	0.686
	<7	2.15 (0.93–4.95)		2.04 (0.06–64.01)

Ref: reference category, indicates statistically significantly associated factors; °c: Degree Celsius.