Admission Outcome and Antimicrobial Resistance Pattern of Bacterial Isolates among Neonates with Suspected Sepsis in Neonatal Intensive Care Unit at Dessie Comprehensive Specialized Hospital, Dessie, Northeastern Ethiopia

Table 5

Distribution of antibiotic resistance from blood cultures of isolated bacteria among neonates with suspected sepsis admitted in NICU at Dessie Comprehensive Specialized Hospital, Dessie, Northeastern Ethiopia, August, 2017 to March, 2018.

Gram-negative bacteria	Antibiotic resistance pattern, n (%)
	AMP	AMC	PTZ	CPM	CAZ	Cxt	CRO	CN	SXT	MEM
E. coli (24)	19 (79.2)	18 (75)	15 (65.6)	11 (45.8)	13 (54.2)	14 (58.3)	14 (58.3)	10 (41.7)	16 (66.7)	2 (8.3)
K. pneumoniae (7)	7 (100)	6 (86)	5 (71.4)	5 (71.4)	5 (71.4)	5 (71.4)	5 (71.4)	4 (57)	7 (100)	1 (14.3)
K. oxytoca (2)	2 (100)	2 (100)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1(50)
Citrobacter sp (2)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)
Acinetobacter sp (1)	NA	NA	1 (100)	1 (100)	1 (100)	1 (100)	1 (100)	0 (0)	1 (100)	0 (0)
Antibiotic resistance pattern, n (%)
Gram-positive bacteria	P	AMP	AMC	FOX	CN	SXT	E	CD
S. aureus (18)	15 (83.3)	15 (83.3)	12 (66.7)	12 (66.7)	4 (22.2)	14 (77.8)	8 (44.4)	1 (5.6)
CoNS (13)	11 (84.6)	11 (84.6)	10 (77)	10 (77)	4 (30.8)	7 (53.8)	4 (30.8)	1 (7.7)

AMP Ampicillin, AMC Amoxicillin-clavulanic acid, CD Clindamycin, CTX Cefotaxime, CAZ Ceftazidime, CPM Cefepime, CRO Ceftriaxone, E Erythromycin, FOX Cefoxitine, CN Gentamicin, MEM Meropenem, PTZ Piperacillin-Tazobactam, P Penicillin, SXT Trimethoprim-Sulfamethoxazole.; NA = NotApplicable; CoNS = Coagulase-negative Staphylococcus spp.