Research Article
Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus
| Characteristics | n = 59 |
| Age (n (%)) | <20 years old | 5 (8.5) | 20–35 years old | 47 (79.7) | >35 years old | 7 (11.9) | Parity (n (%)) | Primigravida | 27 (45.8) | Multigravida | 32 (54.2) | Gestational age (n (%)) | Preterm | 8 (13.6) | Term | 44 (74.6) | Postterm | 7 (11.9) | Placental disorders (n (%)) | Placenta previa | 1 (1.7) | Placental abruption | 0 | Preeclampsia | 2 (3.4) | Premature rupture of the membrane (n (%)) | 3 (5.1) | Fetal distress (n (%)) | 1 (1.7) | Delivery mode (n (%)) | Vaginal delivery | 47 (79.7) | Cesarean section | 12 (20.3) | Maternal serological factors | HBsAg titer (n (%)) | <1000 IU/ml | 36 (61) | >1000 IU/ml | 23 (39) | HBV DNA (n (%)) | Negative | 7 (11.8) | Positive | 52 (88.1) | HBeAg (n (%)) | Negative | 43 (72.9) | Positive | 16 (27.1) | Anti-HBs (n (%)) | Negative | 56 (94.9) | Positive | 3 (5.1) | Anti-HBc (n (%)) | Negative | 21 (35.6) | Positive | 38 (64.4) | Viral load (n (%)) | <5.3 log 10 IU/ml | 52 (88.1) | 5.3 log 10 IU/ml | 7 (11.8) | Intrauterine exposure of hepatitis B (n (%)) | HBV DNA cord blood negative | 18 (30.5) | HBV DNA cord blood positive | 41 (69.5) | TLR2 expression in placenta tissue (n (%)) | Score 0 | 5 (8.5) | Score 1 | 15 (25.4) | Score 2 | 15 (25.4) | Score 3 | 24 (40.7) |
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