Review Article

Stunting as a Risk Factor of Soil-Transmitted Helminthiasis in Children: A Literature Review

Table 4

Summary of laboratory findings in various studies.

Type of diseaseLaboratory FindingsEffect Size-valueRef

StuntingAlpha 1-antitrypsin median (μg/g):βa = 0.410.044[27]
Stunting = 236.6
Normal = 151.4
The proportion of IgA-coated bacteria in feces is higher.N/A0.029[31]

AscariasisRetinol binding protein <0.7 mg/LaPRb = 2.20[22]
Geometric mean EPG (eggs per Gram):[17]
7–9 months = 1.1
12–14 months = 2.4
Geometric mean EPG = 2.2[24]
EPG is higher in stunted children under five years of age.IRRc = 0.15<0.001[20]

TrichuriasisGeometric mean EPG:[17]
7–9 months = 1.1
12–14 months = 3.1
Geometric mean EPG = 1.3[24]

Hookworm infectionEPG is higher in the second infection in stunted children under five years of age.IRR = 0.49<0.06[20]
Geometric mean EPG:[17]
7–9 months = 1.1
12–14 months = 1.0
Geometric mean EPG = 1.0[24]

Ascariasis/Trichuriasis coinfectionFerritin <12 mg/LaPR = 3.28[22]

Environmental enteropathyThe intestinal inflammatory biomarker myeloperoxidase decreased as the age increased.Coefficient: −0.290.002[28]

aRegression coefficient. bAdjusted prevalence ratio. cIncidence rate ratio.