Table 1: Symptoms and detection of S-OIV.

Date (2009) Sep 16 17 18 19 20 21 22 23 24 25 26 27 28 Time (day) 1 2 3 4 5 6 7 8 9 10 11 12 13 Oseltamivir +1 ++ ++ ++ ++ + Real-time RT-PCR +++ ++ + + + + − − RT-PCR + + + + + + − − Virus isolation +2 +3 − − − − − − Fever (>38.5°C) − + + − − − − − − − Sore throat + + + + + +++ +++ +++ ++ − − − Headache − − + + ++ ++ +++ +++ + − − − Cough − − + + + +++ +++ +++ ++ + ± −

1Seventy-five mg of oseltamivir. The first tablet was administered around 21:00. 2Pharyngeal swab was taken around 17:00 (20 h after oseltamivir administration). 3Pharyngeal swab was taken around 17:00 (44 h after oseltamivir administration).