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Influenza Research and Treatment
Volume 2011 (2011), Article ID 206975, 7 pages
http://dx.doi.org/10.1155/2011/206975
Research Article

Experiences after Twenty Months with Pandemic Influenza A (H1N1) 2009 Infection in the Naïve Norwegian Pig Population

1Department of Laboratory Services, Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106 Oslo, Norway
2Department of Health Surveillance, Norwegian Veterinary Institute, P.O. Box 750 Sentrum, 0106 Oslo, Norway
3Department of Control, Norwegian Food Safety Authority, Kyrkjevegen 332, 4325 Sandnes, Norway
4Norwegian Pig Health Service, Animalia, P.O. Box 396 Økern, 0513 Oslo, Norway
5Division of Infectious Disease Control, Department of Virology, Norwegian Institute of Public Health, P.O. Box 4404 Nydalen, 0403 Oslo, Norway

Received 15 September 2011; Revised 21 November 2011; Accepted 18 December 2011

Academic Editor: Montserrat Torremorell

Copyright © 2011 B. Gjerset et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. Van Reeth, I. H. Brown, R. Dürrwald et al., “Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002-2003,” Influenza and other Respiratory Viruses, vol. 2, no. 3, pp. 99–105, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. J. Maldonado, K. Van Reeth, P. Riera et al., “Evidence of the concurrent circulation of H1N2, H1N1 and H3N2 influenza A viruses in densely populated pig areas in Spain,” Veterinary Journal, vol. 172, no. 2, pp. 377–381, 2006. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  3. I. H. Brown, “The epidemiology and evolution of influenza viruses in pigs,” Veterinary Microbiology, vol. 74, no. 1-2, pp. 29–46, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. R. J. Garten, C. T. Davis, C. A. Russell et al., “Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans,” Science, vol. 325, no. 5937, pp. 197–201, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  5. J. Cohen, “Swine flu outbreak. New details on virus's promiscuous past,” Science, vol. 324, no. 5931, p. 1127, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. S. E. Forgie, J. Keenliside, C. Wilkinson et al., “Swine outbreak of pandemic influenza A virus on a canadian research farm supports human-to-swine transmission,” Clinical Infectious Diseases, vol. 52, no. 1, pp. 10–18, 2011. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. A. Moreno, T. L. Di, L. Alborali , et al., “First pandemic H1N1 outbreak from a pig farm in Italy,” The Open Virology Journal, vol. 4, pp. 52–56, 2010.
  8. T. Pasma and T. Joseph, “Pandemic (H1N1) 2009 infection in swine herds, Manitoba, Canada,” Emerging Infectious Diseases, vol. 16, no. 4, pp. 706–708, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  9. M. D. Welsh, P. M. Baird, M. P. Guelbenzu-Gonzalo et al., “Initial incursion of pandemic (H1N1) 2009 influenza A virus into European pigs,” Veterinary Record, vol. 166, no. 21, pp. 642–645, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. M. Hofshagen, B. Gjerset, and C. Er, “Pandemic influenza A(H1N1)v: human to pig transmission in Norway?” Euro Surveillance, vol. 14, no. 45, 2009.
  11. S. M. Brookes, A. Núñez, B. Choudhury et al., “Replication, pathogenesis and transmission of pandemic (H1N1) 2009 virus in non-immune pigs,” PLoS One, vol. 5, no. 2, Article ID e9068, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. P. K. Holyoake, P. D. Kirkland, R. J. Davis et al., “The first identified case of pandemic H1N1 influenza in pigs in Australia,” Australian Veterinary Journal, vol. 89, no. 11, pp. 427–431, 2011. View at Publisher · View at Google Scholar · View at PubMed
  13. N. Busquets, J. Segalés, L. Córdoba et al., “Experimental infection with H1N1 European swine influenza virus protects pigs from an infection with the 2009 pandemic H1N1 human influenza virus,” Veterinary Research, vol. 41, no. 5, article 74, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. E. Lange, D. Kalthoff, U. Blohm et al., “Pathogenesis and transmission of the novel swine-origin influenza virus A/H1N1 after experimental infection of pigs,” Journal of General Virology, vol. 90, no. 9, pp. 2119–2123, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. A. L. Vincent, K. M. Lager, K. S. Faaberg et al., “Experimental inoculation of pigs with pandemic H1N1 2009 virus and HI cross-reactivity with contemporary swine influenza virus antisera,” Influenza and other Respiratory Viruses, vol. 4, no. 2, pp. 53–60, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. C. S. Kyriakis, C. W. Olsen, S. Carman et al., “Serologic cross-reactivity with pandemic (H1N1) 2009 virus in pigs, Europe,” Emerging Infectious Diseases, vol. 16, no. 1, pp. 96–99, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  17. B. Lium, A. Germundsson, C. Er, and P. Hopp, “The surveillance and control programme for specific virus infections in swine herds in Norway,” in Surveillance and control programmes for terrestrial and aquatic animals in Norway, annual report 2010, pp. 1–8, National Veterinary Institute, 2011.
  18. B. Lium, A. Jorgensen, and M. Gjestvang, “The Norwegian program for eradication of Mycoplasma hyopneumoniae is successfully completed,” in Proceedings of the 21st IPVS Congress, p. 643, 2010.
  19. Office International des Epizooties, Manual of standards for diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees), vol. 1, 6th edition, 2010.
  20. World Health Organization, The WHO Collaborating Centre for influenza at CDC Atlanta,United States of America. CDC protocol of realtime RTPCR for influenza A(H1N1), WHO, Atlanta, Ga, USA, 2009, http://www.who.int/csr/resources/publications/swineflu/CDCRealtimeRTPCR_SwineH1Assay-2009_20090430.pdf.
  21. Robert Koch-Institut, “TagMan real-time PCR zur Detektion von porcinen Influenza A/H1N1-Viren. Empfehlung für den Nachweis der porcinen Influenza A/H1N1-Viren mittels real-time PCR,” 2010, http://www.rki.de/cln_160/nn_200120/DE/Content/InfAZ/I/Influenza/IPV/Schweinegrippe__PCR.html.
  22. World Health Organization, The WHO Collaborating Centre for influenza at CDC Atlanta, United States of America. Sequencing primers and protocol, WHO, Atlanta, Ga, USA, 2009, http://www.who.int/entity/csr/resources/publications/swineflu/GenomePrimers_20090512.pdf.
  23. T. A. Hall, “BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT,” pp. 95–98, 1999.
  24. K. Waalen, A. Kilander, S. G. Dudman, G. H. Krogh, T. Aune, and O. Hungnes, “High prevalence of antibodies to the 2009 pandemic influenza A(H1N1) virus in the Norwegian population following a major epidemic and a large vaccination campaign in autumn 2009,” Eurosurveillance, vol. 15, no. 31, 2010. View at Scopus
  25. R. Tellier, “Aerosol transmission of influenza A virus: a review of new studies,” Journal of the Royal Society Interface, vol. 6, no. 6, pp. S783–S790, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  26. I. A. Gardner, P. Willeberg, and J. Mousing, “Empirical and theoretical evidence for herd size as a risk factor for swine diseases,” Animal Health Research Reviews, vol. 3, no. 1, pp. 43–55, 2002. View at Scopus
  27. K. M. Grebe, J. W. Yewdell, and J. R. Bennink, “Heterosubtypic immunity to influenza A virus: where do we stand?” Microbes and Infection, vol. 10, no. 9, pp. 1024–1029, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  28. K. Van Reeth, V. Gregory, A. Hay, and M. Pensaert, “Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes,” Vaccine, vol. 21, no. 13-14, pp. 1375–1381, 2003. View at Publisher · View at Google Scholar · View at Scopus
  29. C. S. Kyriakis, I. H. Brown, E. Foni et al., “Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008,” Zoonoses and Public Health, vol. 58, no. 2, pp. 93–101, 2011. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  30. W. A. Howard, S. C. Essen, B. W. Strugnell et al., “Reassortant pandemic (H1N1) 2009 virus in pigs, United Kingdom,” Emerging Infectious Diseases, vol. 17, no. 6, pp. 1049–1052, 2011. View at Publisher · View at Google Scholar
  31. Y. Bi, G. Fu, J. Chen et al., “Novel swine influenza Virus reassortants in Pigs, China,” Emerging Infectious Diseases, vol. 16, no. 7, pp. 1162–1164, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  32. P. Kitikoon, D. Sreta, S. Nuntawan Na Ayudhya et al., “Brief report: molecular characterization of a novel reassorted pandemic H1N1 2009 in Thai pigs,” Virus Genes, vol. 43, no. 1, pp. 1–5, 2011. View at Publisher · View at Google Scholar · View at PubMed
  33. D. Vijaykrishna, L. L. M. Poon, H. C. Zhu et al., “Reassortment of pandemic H1N1/2009 influenza a virus in swine,” Science, vol. 328, no. 5985, p. 1529, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus