Monoclonal Antibody Targeting Neutralizing Epitope on H5N1 Influenza Virus of Clade 1 and 0 for Specific H5 Quantification
Table 1
HI and virus neutralization activity of Mab 11G12a.
Virus
Clade
HI titerb
VN titerc
A/HongKong/156/97
0
112
160
A/VietNam/1203/04
1.0
256
320
A/HongKong/213/2004
1.0
256
320
A/Indonesia/CDC594/06
2.1.2
<4
<10
A/Indonesia/CDC669/06
2.1.3
<4
<10
A/Nigeria/6e/07
2.2
<4
<10
A/chicken/Guangdong/178/04
2.2
<4
<10
A/Anhui/1/05
2.3
<4
<10
A/Jiangsu/2/07
2.3
<4
<10
A/goose/Guiyang/337/06
4
<4
<10
A/chicken/Shanxi/2/06
7
<4
<10
A/chicken/Henan/12/04
8
<4
<10
aConcentration of MAb at 0.5 mg/mL.
b4 HA unit of each virus strain used for HI.
cOne hundred TCID50 of each virus strain used for microneutralization assays.
