Research Article

Effective Single-Step Posttranscriptional Dynamics Allowing for a Direct Maximum Likelihood Estimation of Transcriptional Activity and the Quantification of Sources of Gene Expression Variability with an Illustration for the Hypoxia and TNFα Regulated Inflammatory Pathway

Figure 3

Transcription rate as measured by the drift coefficient (a), strength of the fluctuating force inducing gene expression variability as measured by the diffusion coefficient (b), and ratio (c) observed under four different stimulation conditions. Error bares indicated standard errors of the means.
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(a)
719138.fig.003b
(b)
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(c)