Table 1: Summary of studies included in the network meta-analysis for CAL gain. SE: standard error; FO: flap operation; GTR-N: guided tissue regeneration with nonresorbable membranes; GTR-R: guided tissue regeneration with resorbable membranes.

StudyMeanSETreatmentStudy design

Sculean et al. 2001 [29]1.700.40FOparallel-group
Sculean et al. 2001 [29] 3.100.40GTR-Rparallel-group
Silvestri et al. 2000 [30] 1.200.33FOparallel-group
Silvestri et al. 2000 [30] 4.800.66GTR-Nparallel-group
Zucchelli et al. 2002 [31] 2.600.15FOparallel-group
Zucchelli et al. 2002 [31] 4.900.29GTR-Nparallel-group
Mayfield et al. 1998 [32] 1.300.40FOparallel-group
Mayfield et al. 1998 [32] 1.500.42GTR-Rparallel-group
Tonetti et al. 1998 [33] 2.180.18FOparallel-group
Tonetti et al. 1998 [33] 3.040.20GTR-Rparallel-group
Cortellini et al. 2001 [34] 2.600.24FOparallel-group
Cortellini et al. 2001 [34] 3.500.28GTR-Rparallel-group
Cortellini et al. 1995 [35] 2.500.46FOparallel-group
Cortellini et al. 1995 [35] 4.700.53GTR-Nparallel-group
Cortellini et al. 1996 [36] 2.300.23FOparallel-group
Cortellini et al. 1996 [36] 5.200.40GTR-Nparallel-group
Cortellini et al. 1996 [36] 4.60.35GTR-Rparallel-group
Paolantonio et al. 2008 [37] 1.500.25FOparallel-group
Paolantonio et al. 2008 [37] 3.100.34GTR-Rparallel-group
Stavropoulos et al. 2003 [38] 1.500.58FOparallel-group
Stavropoulos et al. 2003 [38] 2.900.54GTR-Rparallel-group
Blumenthal and Steinberg 1990 [39] 0.750.06FOsplit-mouth
Blumenthal and Steinberg 1990 [39] 1.170.03GTR-Rsplit-mouth
Pritlove-Carson et al. 1995 [40] 1.730.36FOsplit-mouth
Pritlove-Carson et al. 1995 [40] 1.780.45GTR-Nsplit-mouth
Ratka-Kr ̈ u ger et al. 2000 [41] 4.000.77FOsplit-mouth
Ratka-Kr ̈ u ger et al. 2000 [41] 4.180.64GTR-Rsplit-mouth
Loos et al. 2002 [42] 1.290.31FOsplit-mouth
Loos et al. 2002 [42] 1.400.28GTR-Rsplit-mouth
Cortellini et al. 1998 [43] 1.600.38FOsplit-mouth
Cortellini et al. 1998 [43] 3.000.35GTR-Rsplit-mouth
Chung et al. 1990 [44] −0.71 0.29FOsplit-mouth
Chung et al. 1990 [44] 0.560.18GTR-Rsplit-mouth
Mora et al. 1996 [45] 2.550.32FOsplit-mouth
Mora et al. 1996 [45] 3.850.28GTR-Nsplit-mouth