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ISRN Dermatology
Volume 2011 (2011), Article ID 241953, 11 pages
http://dx.doi.org/10.5402/2011/241953
Clinical Study

Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA

Hair Cynr-G Inc., 11500 West Olympic Boulevard, No. 630, Los Angeles, CA 90064, USA

Received 8 February 2011; Accepted 16 March 2011

Academic Editor: A. R. Ercocen

Copyright © 2011 A. W. Rafi and R. M. Katz. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. M. Mella, M. C. Perret, M. Manzotti, H. N. Catalano, and G. Guyatt, “Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review,” Archives of Dermatology, vol. 146, no. 10, pp. 1141–1150, 2010. View at Publisher · View at Google Scholar · View at PubMed
  2. J. A. Ellis, R. Sinclair, and S. B. Harrap, “Androgenetic alopecia: pathogenesis and potential for therapy,” Expert Reviews in Molecular Medicine, vol. 4, pp. 1–11, 2002. View at Scopus
  3. O. T. Norwood, Hair Transplant Surgery, Charles C Thomas Publishers, Springfield, Ill, USA, 1973.
  4. R. J. Rajput, “Controversy: is there a role for adjuvants in the management of male pattern hair loss?” Journal of Cutaneous and Aesthetic Surgery, vol. 3, no. 3, pp. 82–86, 2010.
  5. E. A. Olsen, M. Hordinsky, D. Whiting et al., “The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: results of a randomized placebo-controlled study of dutasteride versus finasteride,” Journal of the American Academy of Dermatology, vol. 55, no. 6, pp. 1014–1023, 2006. View at Publisher · View at Google Scholar · View at PubMed
  6. E. Olsen, “Pattern hair loss,” in Disorders of Hair Growth. Diagnosis and Treatment, pp. 321–362, McGraw Hill, New York, NY, USA, 2003.
  7. R. Sinclair, “Fortnightly review. Male pattern androgenetic alopecia,” British Medical Journal, vol. 317, no. 7162, pp. 865–869, 1998. View at Scopus
  8. D. A. Whiting, “Male pattern hair loss: current understanding,” International Journal of Dermatology, vol. 37, no. 8, pp. 561–566, 1998. View at Publisher · View at Google Scholar · View at Scopus
  9. J. D. Wilson, J. E. Griffin, and D. W. Russell, “Steroid 5α-reductase 2 deficiency,” Endocrine Reviews, vol. 14, no. 5, pp. 577–593, 1993. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Piérard-Franchimont, P. De Doncker, G. Cauwenbergh, and G. E. Piérard, “Ketoconazole shampoo: effect of long-term use in androgenic alopecia,” Dermatology, vol. 196, no. 4, pp. 474–477, 1998. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Downs, “Nizoral shampoo for hair loss,” DERMAdoctor, http://www.dermadoctor.com/article_Nizoral-Shampoo-for-Hair-Loss_198.html.
  12. J. Jiang, R. Tsuboi, Y. Kojima, and H. Ogawa, “Topical application of ketoconazole stimulates hair growth in C3H/HeN mice,” Journal of Dermatology, vol. 32, no. 4, pp. 243–247, 2005. View at Scopus
  13. M. Hiruma, D. J. Maeng, M. Kobayashi, H. Suto, and H. Ogawa, “Fungi and atopic dermatitis,” Nihon Ishinkin Gakkai Zasshi, vol. 40, no. 2, pp. 79–83, 1999. View at Scopus
  14. H. C. Eun, O. S. Kwon, J. H. Yeon et al., “Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: a randomized, double-blind, placebo-controlled, phase III study,” Journal of the American Academy of Dermatology, vol. 63, no. 2, pp. 252–258, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. T. Sato, T. Sonoda, S. Itami, and S. Takayasu, “Predominance of type I 5α-reductase in apocrine sweat glands of patients with excessive or abnormal odour derived from apocrine sweat (osmidrosis),” British Journal of Dermatology, vol. 139, no. 5, pp. 806–810, 1998. View at Publisher · View at Google Scholar · View at Scopus
  16. D. Thiboutot, G. Harris, V. Iles, G. Cimis, K. Gilliland, and S. Hagari, “Activity of the type 1 5α-reductase exhibits regional differences in isolated sebaceous glands and whole skin,” Journal of Investigative Dermatology, vol. 105, no. 2, pp. 209–214, 1995. View at Scopus
  17. E. P. Jenkins, S. Andersson, J. Imperato-McGinley, J. D. Wilson, and D. W. Russell, “Genetic and pharmacological evidence for more than one human steroid 5α-reductase,” Journal of Clinical Investigation, vol. 89, no. 1, pp. 293–300, 1992. View at Scopus
  18. D. W. Russell and J. D. Wilson, “Steroid 5α-reductase: two genes/two enzymes,” Annual Review of Biochemistry, vol. 63, pp. 25–61, 1994. View at Scopus
  19. A. E. Thigpen, R. I. Silver, J. M. Guileyardo, M. L. Casey, J. D. McConnell, and D. W. Russell, “Tissue distribution and ontogeny of steroid 5α-reductase isozyme expression,” Journal of Clinical Investigation, vol. 92, no. 2, pp. 903–910, 1993. View at Scopus
  20. R. V. Clark, D. J. Hermann, G. R. Cunningham, T. H. Wilson, B. B. Morrill, and S. Hobbs, “Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5α-reductase inhibitor,” Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 5, pp. 2179–2184, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. R. M. Trüeb, “Association between smoking and hair loss: another opportunity for health education against smoking?” Dermatology, vol. 206, no. 3, pp. 189–191, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  22. J. G. Mosley and A. C. C. Gibbs, “Premature grey hair and hair loss among smokers: a new opportunity for health education?” British Medical Journal, vol. 313, no. 7072, p. 1616, 1996. View at Scopus
  23. M. Musquera, N. E. Fleshner, A. Finelli, and A. R. Zlotta, “The REDUCE trial: chemoprevention in prostate cancer using a dual 5α-reductase inhibitor, dutasteride,” Expert Review of Anticancer Therapy, vol. 8, no. 7, pp. 1073–1079, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  24. B. J. Schmitz-Dräger, C. Fischer, E. Bismarck, H. J. Dörsam, and G. Lümmen, “The prostate cancer prevention trial (PCPT): relevance for clinical practice,” Der Urologe A, vol. 46, no. 10, pp. 1364–1370, 2007. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus