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ISRN Dermatology
Volume 2012 (2012), Article ID 163929, 3 pages
http://dx.doi.org/10.5402/2012/163929
Research Article

Treatment of Plane Warts with a Low-Dose Oral Isotretinoin

1Department of Dermatology and Venereology, College of Medicine, University of Baghdad, Medical Collection Office, P.O. Box 61211, Baghdad 12114, Iraq
2Department of Dermatology and Venereology, Baghdad Teaching Hospital, Medical City, Baghdad, Iraq

Received 22 September 2012; Accepted 21 November 2012

Academic Editors: A. Ingber and A. Zalewska

Copyright © 2012 Hayder R. Al-Hamamy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To assess the efficacy of a low-dose oral isotretinoin in the treatment of plane warts. Patients and Methods. Thirty-one patients with recalcitrant facial plane warts were enrolled. A cumulative dose of 30 mg/kg for two months of treatment was calculated; this was equal to a mean of 0.5 mg/kg/day. Each patient was seen every two weeks during the treatment period. Response to treatment was either complete or no response. Patients with complete response were followed up monthly for four months to record the relapse rate. Results. Twenty-six patients completed the study; their ages range from 5 to 35 with a mean ± SD years. Fifteen (57.69%) patients were females and eleven (42.30%) were males. Nineteen (73.07%) patients showed complete response and seven (26.92%) patients showed no response at the end of two months of therapy. The difference was statistically significant; P value . Fifteen (78.94%) out of nineteen patients, who had complete response, were still free from warts at the end of four-month followup. Conclusion. Oral isotretinoin is effective in the treatment of recalcitrant facial plane warts.