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ISRN Dermatology
Volume 2012 (2012), Article ID 679619, 4 pages
http://dx.doi.org/10.5402/2012/679619
Clinical Study

Cutaneous Manifestations in Patients with Chronic Kidney Disease on Maintenance Hemodialysis

1Department of Nephrology, Narayana Medical College Hospital, Chinthareddypalem, Nellore 524002, India
2Department of Clinical Pharmacology, Narayana Medical College Hospital, Chinthareddypalem, Nellore 524002, India
3Department of Radiology, Narayana Medical College Hospital, Chinthareddypalem, Nellore 524002, India
4Department of Dermatology, Narayana Medical College Hospital, Chinthareddypalem, Nellore 524002, India

Received 10 April 2012; Accepted 16 May 2012

Academic Editors: E. Alpsoy and C. Feliciani

Copyright © 2012 Praveen Kumar Kolla et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cutaneous disorders can precede or follow the initiation of hemodialysis treatment. We evaluated the prevalence of various dermatological manifestations in patients undergoing hemodialysis at least twice a week for minimum of three months at our center. Patients were excluded if they were undergoing hemodialysis less than twice a week or on hemodialysis secondary to ESRD following graft dysfunction. One hundred and forty-three patients were evaluated. Among them, there were 113 male and 30 females. Among the skin changes, pruritus accounted for 56%, Xerosis was observed in 52%, Diffuse blackish hyper pigmentation was seen in 40%. Skin infections was seen in 53% of patients, of these fungal, bacterial and viral infections were 27.2%, 14.6%, and 11.2%, respectively. Kyrle’s disease was observed only in 6.9%. Other skin manifestations include eczema 4.8%, psoriasis 2.7%, and drug rash 2.1%. Nail changes were observed in 46 patients of whom 27 patients had onychomycosis. Other changes include discoloration, onycholysis, and splinter hemorrhages. Hair changes were observed in 21.7%. Mucosal changes were seen in 27.3%. In our study, pruritus, xerosis, and pigmentation were higher among skin changes. Recognition and management of some of these dermatological manifestations vastly reduce the morbidity and improve the quality of life.