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ISRN Dermatology
Volume 2014 (2014), Article ID 271230, 6 pages
http://dx.doi.org/10.1155/2014/271230
Clinical Study

Anolunula in Fingernails among Patients Infected with HIV

1Department of Dermatology, SRMSIMS, Bareilly, Uttar Pradesh 243001, India
2Department of Pediatrics, SRMSIMS, Bareilly, Uttar Pradesh 243001, India
3Care Hospital, Hyderabad, India

Received 26 November 2013; Accepted 17 December 2013; Published 23 February 2014

Academic Editors: S. Husz, J. C. Szepietowski, and J. F. Val-Bernal

Copyright © 2014 Pratik Gahalaut et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Lunula is the white, half-moon shaped area seen in proximal ends of some nails. Though a few studies have described the nail changes that can occur in association with HIV infection, none of these paid much attention to lunula. Aims and Objectives. To study the lunula in fingernails among HIV infected patients. Materials and Methods. An observational, cross-sectional study to record presence of lunula in 168 HIV-positive patients and compare it with age and sex matched 168 healthy HIV-negative control. Anolunula (absence of lunula) in HIV-positive patients was correlated with CD4 counts, stages of HIV infection, time since patient was diagnosed as HIV-positive, and status of antiretroviral therapy. Results. Anolunula was present in significantly more fingernails in HIV-positive patients compared to HIV-negative controls. There was a highly significant difference for total anolunula (anolunula in all fingernails) in study and control group. Incidence of total anolunula was directly proportional to the stage of HIV infection, increasing progressively as the HIV infection advances from stage 1 to stage 4. Conclusion. Absence of lunula is related to not only HIV infection per se but also the stages of HIV infection.