Table 1: Characteristics of wild-type (WT) and ob/ob (OB) mice receiving an AIN-93G diet (AIN) or a sterculic oil-supplemented diet (SO)1.

value2
WT AINWT SOOB AINOB SOdgd × g

Body weight (g)24.0 ± 0.525.2 ± 1.048.6 ± 1.148.5 ± 0.90.554<0.0010.471
Food intake3 (g/day)2.7 ± 0.12.9 ± 0.14.1 ± 0.24.1 ± 0.40.582<0.0010.908
Tissue weights (g)
 Gonadal AT40.4 ± 0.00.5 ± 0.13.1 ± 0.13.8 ± 0.1¥<0.001<0.0010.005
 Subcutaneous AT0.3 ± 0.00.4 ± 0.03.4 ± 0.13.5 ± 0.10.320<0.0010.828
 Perirenal AT0.1 ± 0.00.1 ± 0.02.1 ± 0.12.3 ± 0.10.375<0.0010.541
 Liver0.8 ± 0.01.0 ± 0.03.4 ± 0.12.8 ± 0.1¥0.031<0.001<0.001
 Liver TG5 (nmol/g wet wt)12.0 ± 3.79.26 ± 2.825.2 ± 7.330.2 ± 8.30.626<0.0010.115
Blood glucose (mg/dL)75.3 ± 5.782.4 ± 6.891.7 ± 6.694.8 ± 11.20.202<0.050.552
Plasma insulin (ng/mL)0.4 ± 0.00.3 ± 0.04.2 ± 0.16.7 ± 1.60.454<0.0010.471

1Data are presented as means ± SEM with = 6-7 per group.
2Data were analyzed by 2-way ANOVA with diet (SO or AIN) as one factor and the phenotype (WT or OB) as the second factor. -values are for an effect of diet (d), and effect of the genotype (g), or an interaction between the two (d × g). When a significant interaction between genotype and diet was found individual means were compared within groups by Bonferroni multiple comparisons.
¥ OB AIN versus OB SO.
3Average daily food intake across the 9 week study.
4AT: adipose tissue.
5TG: triglyceride.