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ISRN Gastroenterology
Volume 2012 (2012), Article ID 480650, 8 pages
http://dx.doi.org/10.5402/2012/480650
Review Article

Transcatheter Arterial Chemoembolization: History for More than 30 Years

1Department of Oncology, West China Hospital of Sichuan University, Chengdu 610041, China
2State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, Chengdu 610041, China

Received 28 June 2012; Accepted 2 August 2012

Academic Editors: A. Amedei and Y. Chao

Copyright © 2012 Yong-Song Guan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Transcatheter arterial chemoembolization (TACE) is a minimally invasive technique to treat liver tumors, particularly hepatocellular carcinoma (HCC). TACE was used in early times to treat liver tumor patients with emergencies caused by symptomatic humoral hypercalcemia and develops gradually from the procedures of diagnostic angiography and transcatheter injection of agents and is in particular performed in the treatment of HCC. Since the beginning of this century, TACE has been used extensively in the palliative treatment of unresectable HCC. In recent years, it is indicated in selected patients with early-stage HCC. This review introduces the evolution of TACE for more than 30 years, its role in comprehensive treatment of HCC, the tendency of its refinement in future, and the combination use of TACE with other local ablative methods for the curative result of HCC.