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ISRN Gastroenterology
Volume 2012 (2012), Article ID 826323, 4 pages
http://dx.doi.org/10.5402/2012/826323
Clinical Study

DNase1: No Association with Crohn's Disease in a New Zealand Population

1Discipline of Nutrition, Faculty of Medical and Health Sciences (FMHS), The University of Auckland, 85 Park Road, Grafton, 1142 Auckland, New Zealand
2Nutrigenomics New Zealand, New Zealand
3Department of Medicine, Faculty of Medical and Health Sciences (FMHS), The University of Auckland, 85 Park Road, Grafton, 1142 Auckland, New Zealand

Received 29 February 2012; Accepted 10 April 2012

Academic Editors: G. Barbaro, J. C. Hoffmann, L. Rodrigo, and I. Takeyoshi

Copyright © 2012 Angharad R. Morgan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. F. Martinez Valle, E. Balada, J. Ordi-Ros, and M. Vilardell-Tarres, “DNase 1 and systemic lupus erythematosus,” Autoimmunity Reviews, vol. 7, no. 5, pp. 359–363, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. F. Martinez-Valle, E. Balada, J. Ordi-Ros, S. Bujan-Rivas, A. Sellas-Fernandez, and M. Vilardell-Tarres, “DNase 1 activity in patients with systemic lupus erythematosus: relationship with epidemiological, clinical, immunological and therapeutical features,” Lupus, vol. 18, no. 5, pp. 418–423, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Belguith-Maalej, H. Hadj-Kacem, N. Kaddour, Z. Bahloul, and H. Ayadi, “DNase1 exon2 analysis in Tunisian patients with rheumatoid arthritis, systemic lupus erythematosus and Sjögren syndrome and healthy subjects,” Rheumatology International, vol. 30, no. 1, pp. 69–74, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Dittmar, C. Bischofs, N. Matheis, R. Poppe, and G. J. Kahaly, “A novel mutation in the DNASE1 gene is related with protein instability and decreased enzyme activity in thyroid autoimmunity,” Journal of Autoimmunity, vol. 32, no. 1, pp. 7–13, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Malíčková, D. Duricová, M. Bortlík, et al., “Impaired deoxyribonuclease I activity in patients with inflammatory bowel diseases,” Autoimmune Diseases, vol. 2011, Article ID 945861, 5 pages, 2011. View at Publisher · View at Google Scholar
  6. K. Yasutomo, T. Horiuchi, S. Kagami et al., “Mutation of DNASE1 in people with systemic lupus erythematosus,” Nature Genetics, vol. 28, no. 4, pp. 313–314, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. J. E. Lennard-Jones, “Classification of inflammatory bowel disease,” Scandinavian Journal of Gastroenterology, Supplement, vol. 24, no. 170, pp. 2–6, 1989. View at Scopus
  8. A. Franke, D. P. McGovern, J. C. Barrett, et al., “Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci,” Nature Genetics, vol. 42, no. 12, pp. 1118–1125, 2010. View at Publisher · View at Google Scholar