Table 2: Relationships between SNPs and subphenotypes.

rs1053874 (tested allele: G)rs8176938 (tested allele: C)
OR (95% CI)POR (95% CI)P

Age at diagnosis<170.86 (0.54–1.36)0.5091.45 (0.45–4.60)0.533
17 to 401.02 (0.81–1.28)0.9001.36 (0.80–2.33)0.259
40<1.08 (0.72–1.62)0.7070.86 (0.39–1.89)0.712

CD behaviourinflammatory1.12 (0.88–1.44)0.3611.27 (0.72–2.22)0.411
stricturing0.78 (0.58–1.06)0.1131.01 (0.53–1.95)0.969
penetrating1.22 (0.74–2.00)0.4332.20 (0.53–9.10)0.275

CD locationIleal0.96 (0.72–1.29)0.8020.86 (0.49–1.52)0.605
Colonic1.11 (0.82–1.51)0.5001.62 (0.74–3.54)0.229
Ileocolonic0.95 (0.69–1.30)0.7261.75 (0.75–4.10)0.195

Other IBD familyY0.89 (0.54–1.48)0.6511.20 (0.37–3.89)0.759
Bowel resectionY0.91 (0.68–1.21)0.5171.43 (0.70–2.91)0.322
EIMY0.89 (0.61–1.32)0.5680.90 (0.41–1.98)0.799
Perianal diseaseY1.33 (0.84–2.10)0.226
SeverityY1.00 (0.69–1.47)0.9821.19 (0.51–2.78)0.695
SmokingY1.08 (0.74–1.58)0.6770.95 (0.34–2.61)0.916