Table 2: Overview of pentraxin receptors.

ReceptorCellsOther ligandsFunctions

FcγRI (CD64)Monocytes, macrophages, DC, inducible on PMNActivating High affinity for IgGAntibody-dependent cell-mediated cytotoxicity
Phagocytosis

FcγRIIA/C (CD32A/C)Monocytes, macrophages, DC neutrophils, plateletsActivatingIgG Antibody-dependent cell-mediated cytotoxicity
Phagocytosis
Platelet activation

FcγRIIB (CD32B)B lymphocytes, macrophages, DCInhibitoryIgGRegulation of responses through immunoreceptors

FcγRIIIA (CD16A)Macrophages, some monocytes, NK cellsActivatingIgGAntibody-dependent cell-mediated cytotoxicity
Phagocytosis

FcγRIIIB (CD16B)PMNsGPI-linkedIgGImmune complex binding
Activation of Fc RIIA

FcαRI (CD89)Monocytes, macrophages, DC neutrophils, plateletsActivating/inhibitoryIgAPhagocytosis
Regulation of responses through other receptors