Table 1: Katanin and other different AAA family microtubule severing proteins.

ProteinSpeciesLength*Domains and length*NCBI accession number

KataninHomo sapiensp60–491
p80–655
p60-PRK04195 (209–265), AAA (241–382), Vps4_C (456–489),
p80-WD40 (7–257), Con80 (492–652)
p60: AAC25114
p80: NP_005877
SpastinHomo sapiens584MIT (116–195),
AAA (313–476)
AAI50261
FidgetinHomo sapiens759AAA (519–654),
Vps4_C (707–756)
NP_060556
LipotransinMus musculus491PRK04195 (211–265)
AAA (241–382)
Vps4_C (456–489)
AAD42087
Katanin-like 1 (KL1) Homo sapiens490AAA (211–380)
Vps4_C (447–488)
NP_001014402
Fidgetin-like 1Homo sapiens674AAA (531–567)
Vps4_C (631–671)
AAH51867
MSP1Saccharomyces cerevisiae362VWA (10–164)
AAA (123–257)
CAA97015
VPS4AHomo sapiens437MIT_VPS4 (4–79)
AAA (130–293)
Vps4_C (373–434)
NP_037377

* All lengths are given in amino acid stretch length in the polypeptide/protein.
(Domain Abbreviations: PRK04195: replication factor C-large subunit, Vps4_C: Vps4 C-terminal oligomerization domain, WD40: beta transducin repeat of 40 aminoacids ending with Tryptophan and Aspartate, MIT: microtubule interacting and trafficking domain, AAA: ATPase associated with diverse cellular activities, VWA: von Willebrand factor type A domain).