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Figure 4: Differential role of the carboxyl- and amino-terminal tails of α 1C in Cav1.2 inactivation. Shown are (a) epifluorescent images illustrating the plasma membrane targeting of the EYFP-labeled α 1C (scaling bars, 4 μm) and (b) superimposed traces of the maximum (black) and (red) scaled to the same amplitude for α 1C- /β 1a/α 2δ [21, 47], (A) PHN-α 1C/α 2δ (B) [47], and ΔN-α 1C/α 2δ (C) [47].