Table 1: Prognostic value of K-RAS mutations.

AuthorTotal number of patientsK-RAS mutations (%)Survival ( 𝑃 - value)

Tsao et al. [24]45026.00.4
Schiller et al. [25]18424.00.38
Graziano et al. [26]21316.40.33
Keohavong et al. [27]173320.74
Lu et al. [28]94340.52
Slebos et al. [29]6927.50.002*
Nelson et al. [30]36522.10.009*
Fukuyama et al. [31]1596.9<0.05*
Huang et al. [32]1448.30.03*
Miyake et al. [33]1878.00.037
Marks et al. [34]29617%NR

NR: not reported.*Statistically significant.