Review Article

K-Ras Mutations in Non-Small-Cell Lung Cancer: Prognostic and Predictive Value

Table 2

Predictive value of K-RAS mutations on overall survival in patients treated with chemotherapy.

AuthorSettingTotal number of patientsK-RAS mutations (%)Survival (HR/ 𝑃 value)

Tsao et al. [24]Adjuvant45026.00.95/0.87
Tsao et al. [37]Adjuvant175119.71.18/0.09
Camps et al. [38]Advanced3088.8NR/0.51
Kalikaki et al. [39]Advanced16222.6NR/0.52

HR: hazard ratio; NR: not reported.