Research Article

Gold-Nanoparticle Decorated Graphene-Nanostructured Polyaniline Nanocomposite-Based Bienzymatic Platform for Cholesterol Sensing

Table 2

Characteristics of ChOx-HRP/NSPANI-AuNP-GR/ITO nanobioelectrode including those reported in the literature.

S. no.Components of biosensorCharacteristicsReferences

(Mat) ChOx-HRP/NSPANI-AuNP-GR/ITO(L) upto 500 mg/dL
(E) ChOx-HRP(S) 4.22 μA mg dL−1 ( ) 0.01 mM
(1)(M) ampero. versus Ag/AgCl(DL) 25 mg/dLPresent investigation
(RT) 19 secs
(SL) 2 months

(Mat) ChOx/f-G/GC(L) upto 135 μM
(2)ChOx/Au/f-G/GC(S) 314 nA/μM cm2[44]
(E) ChOx(SL) 1 month
(M) ampero. versus Ag/AgCl

(Mat) ChOx/NSPANI-SDS(L) 05–10.5 mM
(E) ChOx(S) 9 mM
(3)(M) photometric( ) 1.32 mM[49]
(RT) 59 secs
(SL) 5 weeks

(Mat) GR-Pt nanoparticle hybrid material(L) up to 12 mM
(4)(E) ChOx, ChEt(S) μA/μM/cm2[44]
(M) ampero. versus Ag/AgCl( ) 5 mM
(DL) 0.2 μM

(Mat) GOx-HRP/MWCNT/PPY/ITO(L) 1–10 mM
(E) GOx, HRP(S) 13.8 mA/μM
(5)(M) ampero. versus Ag/AgCl( ) 0.52 mM[50]
(DL) 0.1 mM
(RT) 10 secs
(SL) 5 weeks

(Mat) ChOx/NanoFe3O4/ITO(L) 2.5–400 mg/dL
(E) ChOx(S) 86 Ω/mg/dL/cm2
(6)(M) ampero. versus Ag/AgCl( ) 0.8 mg/dL[51]
(DL) 0.25 mg/dL
(RT) 25 secs
(SL) 55 days

(Mat) ChEt-ChOx/MWCNT/SiO2-CHIT/ITO(L) 10–500 mg/dL
(E) ChEt-ChOx(S) 2.12 μA/mM
(7)(M) ampero. versus Ag/AgCl( ) 0.052 mM[52]
(DL) 0.1 mM
(RT) 10 secs
(SL) 10 weeks

(Mat) ChOx/PANI-NS/ITO(L) 25–500 mg/dL
(E) ChOx(S)  mA mg−1dL
(8)(M) ampero. versus Ag/AgCl( ) 2.5 mM[53]
(RT) 10 secs
(SL) 12 weeks

(Mat) material; (E): enzyme; (M): method; (DL): detection limit; (L): linearity; (SL): shelf life; (RT): response time; (S): sensitivity; ( ): Michaelis-Menton constant; (f-G): functionalized graphene nanoplatelets; (Au/f-G): gold-nanoparticle-decorated f-G; (NSPANI): nanostructured polyaniline; (SDS): sodium dodecyl sulphate; (MWCNT/PPY/ITO): carboxy-modified multiwalled carbon nanotubes (MWCNT) and polypyrrole (PPY) nanocomposite film; (NanoFe3O4): nanostructured iron oxide; (SiO2): silica; (CHIT): chitosan; (PANI-NS): polyaniline nanospheres.