Research Article
Gold-Nanoparticle Decorated Graphene-Nanostructured Polyaniline Nanocomposite-Based Bienzymatic Platform for Cholesterol Sensing
Table 2
Characteristics of ChOx-HRP/NSPANI-AuNP-GR/ITO nanobioelectrode including those reported in the literature.
| S. no. | Components of biosensor | Characteristics | References |
| | (Mat) ChOx-HRP/NSPANI-AuNP-GR/ITO | (L) upto 500 mg/dL | | | (E) ChOx-HRP | (S) 4.22 μA mg dL−1 () 0.01 mM | | (1) | (M) ampero. versus Ag/AgCl | (DL) 25 mg/dL | Present investigation | | | (RT) 19 secs | | | | (SL) 2 months | |
| | (Mat) ChOx/f-G/GC | (L) upto 135 μM | | (2) | ChOx/Au/f-G/GC | (S) 314 nA/μM cm2 | [44] | (E) ChOx | (SL) 1 month | | (M) ampero. versus Ag/AgCl | | |
| | (Mat) ChOx/NSPANI-SDS | (L) 05–10.5 mM | | | (E) ChOx | (S) 9 mM | | (3) | (M) photometric | () 1.32 mM | [49] | | | (RT) 59 secs | | | | (SL) 5 weeks | |
| | (Mat) GR-Pt nanoparticle hybrid material | (L) up to 12 mM | | (4) | (E) ChOx, ChEt | (S) μA/μM/cm2 | [44] | (M) ampero. versus Ag/AgCl | () 5 mM | | | (DL) 0.2 μM | |
| | (Mat) GOx-HRP/MWCNT/PPY/ITO | (L) 1–10 mM | | | (E) GOx, HRP | (S) 13.8 mA/μM | | (5) | (M) ampero. versus Ag/AgCl | () 0.52 mM | [50] | | (DL) 0.1 mM | | | (RT) 10 secs | | | | (SL) 5 weeks | |
| | (Mat) ChOx/NanoFe3O4/ITO | (L) 2.5–400 mg/dL | | | (E) ChOx | (S) 86 Ω/mg/dL/cm2 | | (6) | (M) ampero. versus Ag/AgCl | () 0.8 mg/dL | [51] | | (DL) 0.25 mg/dL | | | (RT) 25 secs | | | | (SL) 55 days | |
| | (Mat) ChEt-ChOx/MWCNT/SiO2-CHIT/ITO | (L) 10–500 mg/dL | | | (E) ChEt-ChOx | (S) 2.12 μA/mM | | (7) | (M) ampero. versus Ag/AgCl | () 0.052 mM | [52] | | (DL) 0.1 mM | | | (RT) 10 secs | | | | (SL) 10 weeks | |
| | (Mat) ChOx/PANI-NS/ITO | (L) 25–500 mg/dL | | | (E) ChOx | (S) mA mg−1dL | | (8) | (M) ampero. versus Ag/AgCl | () 2.5 mM | [53] | | | (RT) 10 secs | | | | (SL) 12 weeks | |
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(Mat) material; (E): enzyme; (M): method; (DL): detection limit; (L): linearity; (SL): shelf life; (RT): response time; (S): sensitivity; (): Michaelis-Menton constant; (f-G): functionalized graphene nanoplatelets; (Au/f-G): gold-nanoparticle-decorated f-G; (NSPANI): nanostructured polyaniline; (SDS): sodium dodecyl sulphate; (MWCNT/PPY/ITO): carboxy-modified multiwalled carbon nanotubes (MWCNT) and polypyrrole (PPY) nanocomposite film; (NanoFe3O4): nanostructured iron oxide; (SiO2): silica; (CHIT): chitosan; (PANI-NS): polyaniline nanospheres.
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