Table 4: Validity of studied markers for preeclampsia in the first and second trimesters.

MarkerCutoff Sensitivity
(95% CI)
Specificity %
(95% CI)
Positive predictive value %
(95% CI)
Negative predictive value %
(95% CI)
Surface under curve
(95% CI)

PAPPA first trimester≤1.6560.0
(49.7–69.7)
78.0
(68.6–85.7)
73.2
(62.2–82.4)
66.1
(56.8–74.6)
0.793
(0.733–0.854)
PP13 first trimester≤88.577.0
(67.5–84.8)
82.0
(73.1–89.0)
81.1
(71.7–88.4)
78.1
(69.0–85.6)
0.879
(0.833–0.924)
PAPPA second trimester≤100.571.0
( 6 1 . 1 = 7 9 . 6 )
71.0
( 6 1 . 1 = 7 9 . 6 )
71.0
( 6 1 . 1 = 7 9 . 6 )
71.0
( 6 1 . 1 = 7 9 . 6 )
0.809
(0.751–0.867)
PP13 second trimester≤315.579.0
(69.7–86.5)
80.0
(70.5–87.3)
79.8
(70.5–87.2)
79.2
(70.0–86.6)
0.876
(0.829–0.924)