Table 1: Descriptive statistics for outcome measures for ALL participants and by diagnostic status* at pre- ( 𝑇 1 ) and post-biopsy ( 𝑇 2 ) visits.

Outcome measure VisitAll participantsBC positive participantsBC negative participants
Mean  ±  SDMean  ±  SDMean  ±  SD

Anxiety subscale of HADS 𝑇 1 8.53  ±  3.63 (n = 38)9.00  ±  2.37 (n = 11)8.33  ±  4.06 (n = 27)
𝑇 2 7.61  ±  3.49 (n = 38)8.46  ±  2.88 (n = 11)7.26  ±  3.71 (n = 27)
Depressive subscale of HADS 𝑇 1 4.66  ±  3.57 (n = 38)3.91  ±  3.08 (n = 11)4.96  ±  3.77 (n = 27)
𝑇 2 4.08  ±  4.05 (n = 38)3.45  ±  3.59 (n = 11)4.33  ±  4.26 (n = 27)
Fatigue (BFI) 𝑇 1 2.78  ±  2.17 (n = 47)2.79  ±  1.34 (n = 15)2.77  ±  2.49 (n = 32)
𝑇 2 2.68  ±  1.99 (n = 47)2.62  ±  1.34 (n = 15)2.70  ±  2.25 (n = 32)
Fatigue level (BFI) 𝑇 1 1.28  ±  0.50 (n = 47)1.20  ±  0.41 (n = 15)1.31  ±  0.54 (n = 32)
𝑇 2 1.26  ±  0.49 (n = 47)1.13  ±  0.35 (n = 15)1.31  ±  0.54 (n = 32)
Sleep (PSQI) 𝑇 1 7.13  ±  3.59 (n = 47)6.60  ±  2.64 (n = 15)7.38  ±  3.97 (n = 32)
𝑇 2 7.15  ±  3.72 (n = 46)6.86  ±  3.94 (n = 14)7.28  ±  3.67 (n = 32)
PANAS positive subscale 𝑇 1 33.17  ±  9.58 (n = 47)33.60  ±  6.48 (n = 15)32.97  ±  10.83 (n = 32)
𝑇 2 33.39  ±  9.30 (n = 46)31.57  ±  7.17 (n = 14)34.19  ±  10.09 (n = 32)
PANAS negative subscale 𝑇 1 21.72  ±  7.75 (n = 47)21.73  ±  7.75 (n = 15)21.72  ±  7.88 (n = 32)
𝑇 2 20.83  ±  7.84 (n = 46)23.21  ±  8.41 (n = 14)19.78  ±  7.48 (n = 32)
Quality of life (EORTC) 𝑇 1 74.82  ±  18.91 (n = 47)77.78  ±  12.86 (n = 15)73.44  ±  21.21 (n = 32)
𝑇 2 71.28  ±  21.69 (n = 47)69.44  ±  15.00 (n = 15)72.14  ±  24.37 (n = 32)
Modified social support (MSSS) 𝑇 1 76.56  ±  22.63 (n = 46)79.58  ±  17.63 (n = 14)75.24  ±  24.64 (n = 32)
𝑇 2 77.52  ±  26.81 (n = 47)89.57  ±  16.77 (n = 15)71.88  ±  28.92 (n = 32)
C-reactive protein (CRP)** 𝑇 1 7248.06  ±  7823.91 (n = 47)6601.80  ±  8583.84 (n = 15)7551.00  ±  7567.07 (n = 32)
𝑇 2 8358.26  ±  8597.71 (n = 47)9696.07  ±  11426.52 (n = 15)7731.16  ±  7032.20 (n=32)
Interleukin-6 (IL-6)** 𝑇 1 348.59  ±  616.14 (n = 34)273.84  ±  472.48 (n = 11)384.34  ±  681.06 (n = 23)
𝑇 2 296.29  ±  556.48 (n = 39)213.49  ±  443.79 (n = 14)342.66  ±  614.32 (n = 25)

BC: breast cancer, *Diagnostic status (BC+ or BC−) was determined after biopsy. It is important to note that participants are not aware of their BC status at the first ( 𝑇 1 ) visit, **Marker on inflammation.